Encontrados 4 documentos, a visualizar página 1 de 1
Genética e Dieta Mediterrânica: Qual o Risco para a Degenerescência Macular da ...
Barreto, Patrícia; Farinha, Cláudia; Coimbra, Rita; Cachulo, Maria Luz; Barbosa Melo , Joana; Lechanteur , Yara; B. Hoyng , Carel; Cunha-Vaz, JoséINTRODUÇÃO: A degenerescência macular da idade (DMI) é uma doença degenerativa da mácula, responsável por perda de visão grave. Factores genéticos e ambientais podem contribuir para a doença. Alguns estudos já sugeriram que a dieta mediterrância pode ser protectora da do- ença, mas o estudo da interacção entre a dieta e a genética é limitado. O nosso objetivo foi avaliar o efeito da adesão à di...
Genetic Associations with Age-related Macular Degeneration and Genetic Risk Sco...
Farinha, Claudia; Barreto, Patrícia; Coimbra, Rita; Cachulo, Maria Luz; Melo, Joana Barbosa; Hoyng, Carel B.; Cunha-Vaz , José; Murta, JoaquimIntroduction: To date several genetic variants are known to play an important role in age-related macular degeneration(AMD). Variations in the genetic pool of different populations impact the disease prevalence, incidence and risk of progression. This report aims to determine the genetic contribution in the development of AMD in a Portuguese population from the Coimbra Eye Study (CES,NCT01298674,NCT02748824), a...
Central Serous Chorioretinopathy: Long-Term Results After Photodynamic Therapy
Sousa Pereira, Pedro Nuno; Ferreira, Sofia Catalão; Soares, Mário; Melo, Pedro; Farinha, Cláudia; Marques, João Pedro; Pires, Isabel; Cachulo, Maria LuzIntroduction: Central serous chorioretinopathy (CSC) is an idiopathic syndrome characterized by neurosensory detachments of the retina. Development of chronic CSC is an indication to treat, and ICGA-guided verteporfin photodynamic therapy has been shown to be very effective. Our objective was to evaluate the 13-year follow-up of chronic CSC patients treated with standard-fluence PDT and to explore the long-te...
EFFICACY AND PROGRESSION OF MACULAR ATROPHY AFTER SEVEN YEARS OF TREATMENT WITH...
Martins, Amélia; Farinha, Cláudia; Santos, Ana Rita; Figueira, João; Pires, Isabel; Cachulo, Maria Luz; Silva, RufinoPURPOSE: To assess the seven-year efficacy of intravitreal ranibizumab (IVR) in the treatment of myopic choroidal neovascularization (mCNV), and to estimate the progression of macular atrophy. MATERIAL AND METHODS: Retrospective study with cross-sectional evaluation. Medical records of high myopic patients with mCNV treated with IVR with minimum follow-up of 84months were analysed. A final cross-sectional evalu...