8 documents found, page 1 of 1

Common and rare genetic risk variants in age-related macular degeneration and g...

Purpose: To determine the contribution of common and rare genetic variants in age-related macular degeneration (AMD) in a Portuguese population from the Coimbra Eye Study (CES), and the genetic risk score (GRS). Methods: Participants underwent ophthalmologic examination and imaging. A centralized reading centre performed AMD staging. Genetic sequencing was carried out with the EYE-RISK assay. Sixty-nine single ...

Interaction between genetics and the adherence to the Mediterranean diet: the r...

Background Age-related macular degeneration (AMD) is a multifactorial degenerative disease of the macula. Different factors, environmental, genetic and lifestyle, contribute to its onset and progression. However, how they interconnect to promote the disease, or its progression, is still unclear. With this work, we aim to assess the interaction of the genetic risk for AMD and the adherence to the Mediterranean d...

A 5-year longitudinal study of macular atrophy

Macular atrophy (MA) is one of the late stages of age-related macular degeneration (AMD) and leads to irreversible loss of visual function. During the past years, efforts have been made towards a more detailed comprehension of the characteristics of MA, and a panel of retina specialists has recently established a new classification system to describe atrophy in the context of neovascular AMD, by the CONAN group...

Age-Related Macular Degeneration Staging by Color Fundus Photography vs. Multim...

Epidemiology of age-related macular degeneration (AMD) is based on staging systems relying on color fundus photography (CFP). We aim to compare AMD staging using CFP to multimodal imaging with optical coherence tomography (OCT), infra-red (IR), and fundus autofluorescence (FAF), in a large cohort from the Epidemiologic AMD Coimbra Eye Study. All imaging exams from the participants of this population-based study...

Nutritional Patterns using Principal Component Analysis and Their Associations ...

EPISCLERAL BRACHYTHERAPY IN PORTUGAL:

OBJECTIVOS: Avaliar o desempenho do Centro de Referência Português de Onco-Oftalmologia no que diz respeito ao controlo local, taxas de sobrevida, taxas de metastização e efeitos secundários da Braquiterapia Episcleral (BTE), e comparar estes resultados com a literatura. MATERIAL E MÉTODOS: Estudo prospectivo e consecutivo que incluiu os doentes referenciados ao Centro de Referência de Onco-Oftamologia por mela...

Adherence to a Mediterranean diet, lifestyle and age-related macular degenerati...

Purpose To characterize the lifestyle and nutritional risk profile associated with the Mediterranean diet in a Portuguese population with and without age‐related macular degeneration (AMD). Methods Nested case–control study (n = 883) within the Coimbra Eye Study, including 434 subjects with AMD and 449 age‐ and sex‐matched subjects without AMD. All enrolled subjects underwent a full risk assessment, including l...

Ocular Risk Factors for Exudative AMD: A Novel Semiautomated Grading System

Purpose. To evaluate the contribution of the ocular risk factors in the conversion of the fellow eye of patients with unilateral exudative AMD, using a novel semiautomated grading system. Materials and Methods. Single-center, retrospective study including 89 consecutive patients with unilateral exudative AMD and ≥3 years of followup. Baseline color fundus photographs were graded using an innovative grading soft...