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Abdominal Hypoperfusion and Acute Kidney Injury in the Critically Ill Patient w...

Pereira, Rui; Lopes, Diogo; Brandão Machado, Sara; Val-Flores, Luís; Caeiro, Fernando; Perdigoto, Rui; Marcelino, Paulo; Saliba, Faouzi

Reduced abdominal perfusion pressure (APP) is an underdiagnosed potential pathophysiological mechanism for acute kidney injury (AKI) in the patient with liver cirrhosis and ascites. This study aimed to analyze the prevalence of abdominal hypoperfusion (AhP) (APP <60 mm Hg) and the impact of APP on AKI in critically ill patients with liver cirrhosis. This was a post hoc analysis from a prospective cohort study s...


Risk Factors of Acute T‐Cell Mediated and Borderline Rejection Diagnosed in Ear...

Roldão, Marisa; Vida, Ana Carlota; Monteiro Dias, Joana; Bigotte Vieira, Miguel; Magriço, Rita; Silva, Cecília; Caeiro, Fernando; Aires, Inês

Introduction: Acute graft rejection remains one of the main causes of graft dysfunction and premature loss. Under‐ standing the factors affecting graft rejection is essential to promote graft survival. Our study aimed to determine the incidence and assess risk factors of acute T‐cell mediated rejection (TCMR) and borderline rejection in early protocol kidney transplant biopsies. Methods: Retrospective single‐ce...


Clinical characteristics and outcomes of PTLD after kidney transplant: a single...

Afonso, Rita; Nicolau, Carla; Vieira, Miguel Bigotte; Caeiro, Fernando; Jorge, Cristina

Post-Transplant Lymphoproliferative Disorder (PTLD) is a serious and potentially fatal complication of immunosuppression in kidney transplantation. Given the rarity of this entity, a high index of suspicion is necessary. We aimed to review the incidence, clinical presentation, histological subtypes, treatment, patient and graft survival of PTLD in kidney transplant patients in our unit.


Acute kidney injury associated with COVID-19 infection : a case report

Duarte, Tiago; Caeiro, Fernando; Góis, Mário; Matos, António; Viana, Lena; Vieira, César; Paulos, Jorge; Paixão, Paulo; Matos, Bruno; Germano, Nuno

SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The...


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