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Citoaderência “in vitro” de eritrócitos de bovinos inoculados com Babesia bovis...
Caetano, Bráulia CostaCoordenação de Aperfeiçoamento de Pessoal de Nível Superior; Eritrócitos de bovinos inoculados com amostras de Babesia bovis (BbovUFV1 7 a passagem e Jaboticabal 7 a passagem, patogênicas e BbovUFV1 26 a passagem, atenuada) foram testados quanto à sua capacidade de aderir em células endoteliais de aorta bovina (BAECs) “in vitro”. Paralelamente, foram realizados ensaios de imunofluorescência indireta com amostra...
Epitope mapping and protective immunity elicited by adenovirus expressing the L...
Resende, Daniela de Melo; Caetano, Bráulia Costa; Dutra, Míriam Santos; Abrantes, Christiane de Freitas; Verly, Rodrigo MoreiraA2was identified as an amastigote virulence factor of Leishmania (Leishmania) donovani and as a candidate antigen for vaccine development against visceral leishmaniasis. Here, predicted hydrophilic, class I and II MHC-binding synthetic peptides were used to define epitopes recognized by A2-specific antibodies, CD8+ T and CD4+ T cells, respectively. Immunization of BALB/c mice with adenovirus expressing A2 (AdA2...
Susceptibility to re-infection in C57BL/6 mice with recombinant strains of Toxo...
Brandão, Geane Peroni; Melo, Maria Norma; Caetano, Bráulia Costa; Carneiro, Cláudia Martins; Silva, Letícia de Azevedo; Vitor, Ricardo Wagner de AlmeidaThis work reports results of re-infection of BALB/c and C57BL/6 mice with different recombinant strains of Toxoplasma gondii. Mice were prime-infected with the non-virulent D8 strain and challenged with virulent strains. PCR–RFLP of cS10-A6 genetic marker of T. gondii demonstrated that BALB/c mice were reinfected with the EGS strain, while C57BL/6 mice were re-infected with the EGS and CH3 strains. Levels of IF...