3 documents found, page 1 of 1
Mayaro virus induction of oxidative stress is associated with liver pathology i...
Caetano, Camila Carla da Silva; Camini, Fernanda Caetano; Almeida, Letícia Trindade; Ferraz, Ariane Coelho; Silva, Tales Fernando daMayaro virus (MAYV) causes Mayaro fever in humans, a self-limiting acute disease, with persistent arthralgia and arthritis. Although MAYV has a remerging potential, its pathogenic mechanisms remain unclear. Here, we characterized a model of MAYV infection in 3–4-week BALB/c mice. We investigated whether the liver acts as a site of viral replication and if the infection could cause histopathological alterations ...
Oxidative stress in Mayaro virus infection.
Camini, Fernanda Caetano; Caetano, Camila Carla da Silva; Almeida, Letícia Trindade; Guerra, Joyce Ferreira da Costa; Silva, Breno de MelloMayaro virus (MAYV) is a neglected tropical arbovirus that causes a febrile syndrome that is sometimes accompanied by incapacitating arthritis/arthralgia. The pathogenesis of MAYV has not been completely defined and oxidative stress mediated by an increase in reactive oxygen species (ROS) and/or depletion of antioxidant defences has been found to contribute to several aspects of viral disease. To investigate wh...
Avaliação do estresse oxidativo e defesas antioxidantes em macrófagos murinos a...
Caetano, Camila Carla da SilvaPrograma de Pós-Graduação em Ciências Biológicas. Núcleo de Pesquisas em Ciências Biológicas, Pró-Reitoria de Pesquisa de Pós Graduação, Universidade Federal de Ouro Preto.; O Mayaro virus (MAYV) é membro da família Togaviridae, gênero Alphavirus. Em humanos, o MAYV causa a Febre Mayaro, doença que apresenta sintomas parecidos com a dengue e outras arboviroses, com exceção das artralgias e artrites persistentes...