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Impact of non-pharmacological interventions on the first wave of COVID-19 in Po...

Bento Loyens, Dinis; Caetano, Constantino; Matias Dias, Carlos

Introduction The COVID-19 pandemic caused over 7 million global deaths. Without vaccines during the first wave, governments implemented nonpharmacological interventions (NPIs) such as lockdowns, school closures, and travel restrictions. This study quantifies the impact of NPIs on COVID-19 transmission in Portugal between 24th February and 1st May. Methods A compartmental SEIR (Susceptible, Exposed, Infectious, ...


Relative vaccine effectiveness against COVID-19 hospitalisation in persons aged...

Fontán-Vela, Mario; Kissling, Esther; Nicolay, Nathalie; Braeye, Toon; Van Evercooren, Izaak; Holm Hansen, Christian; Emborg, Hanne-Dorthe

Since 2021, the Vaccine Effectiveness, Burden and Impact Studies of coronavirus disease 2019 (COVID-19) and influenza (VEBIS) project monitors vaccine effectiveness (VE) in real-world conditions to inform vaccination programmes in the European Union/European Economic Area (EU/EEA) countries [1]. One project aims to monitor real-time COVID-19 VE using electronic health registries (EHR) in multiple countries, wit...


Social contact patterns during the COVID-19 pandemic in 21 European countries -...

Wong, Kerry L.M.; Gimma, Amy; Coletti, Pietro; Paolotti, Daniela; Tizzani, Michele; Cattuto, Ciro; Schmidt, Andrea; Gredinger, Gerald; Stumpfl, Sophie

Background: Most countries have enacted some restrictions to reduce social contacts to slow down disease transmission during the COVID-19 pandemic. For nearly two years, individuals likely also adopted new behaviours to avoid pathogen exposure based on personal circumstances. We aimed to understand the way in which different factors affect social contacts - a critical step to improving future pandemic responses...


Pregnancy during COVID-19: social contact patterns and vaccine coverage of preg...

Wong, Kerry L.M.; Gimma, Amy; Paixao, Enny; Paolotti, Daniela; Karch, André; Jäger, Veronika; Baruch, Joaquin; Melillo, Tanya; Hudeckova, Henrieta

Background: Evidence and advice for pregnant women evolved during the COVID-19 pandemic. We studied social contact behaviour and vaccine uptake in pregnant women between March 2020 and September 2021 in 19 European countries. Methods: In each country, repeated online survey data were collected from a panel of nationally-representative participants. We calculated the adjusted mean number of contacts reported wit...


Mathematical Modelling of the Impact of Non-Pharmacological Strategies to Contr...

Caetano, Constantino; Morgado, Maria Luísa; Patrício, Paula; Pereira, João E.; Nunes, Baltazar

In this paper, we present an age-structured SEIR model that uses contact patterns to reflect the physical distance measures implemented in Portugal to control the COVID-19 pandemic. By using these matrices and proper estimates for the parameters in the model, we were able to ascertain the impact of mitigation strategies employed in the past. Results show that the March 2020 lockdown had an impact on disease tra...


Métodos epidemiológicos e estatísticos numa emergência de Saúde Pública

Nunes, Baltazar; Caetano, Constantino; Antunes, Liliana; Torres, Ana Rita; Silva, Susana; Rodrigues, Ana Paula; Kislaya, Irina; Machado, Ausenda

Sobre o papel dos método estatístico e epidemiológico na resposta à emergência COVID-19: Vigilância epidemiológica; Estudos epidemiológicos especiais; Modelação matemática.


Statistics in Times of Pandemics: the Role of Statistical and Epidemiological M...

Nunes, Baltazar; Caetano, Constantino; Antunes, Liliana; Torres, Ana Rita; Silva, Susana; Rodrigues, Ana Paula; Kislaya, Irina; Machado, Ausenda

About the Role of Statistical and Epidemiological Methods during the COVID-19 Emergency.


Frequência de Mutações de Resistência aos ARVs em novos casos de infeção por VI...

Aldir, Isabel; Cortes Martins, Helena; Caetano, Constantino; Sarmento, António; Serrão, Rosário; Saraiva da Cunha, José; Oliveira, Joaquim

Introdução: A avaliação da presença de mutações que confiram resistência aos fármacos usados no tratamento da infeção por VIH-1, faz parte da avaliação laboratorial efetuada no quadro de um diagnóstico de novo, e a monitorização da sua prevalência é preconizada internacionalmente. Objetivos: Avaliar a frequência de mutações de resistência (MR) entre doentes com diagnóstico estabelecido em 2018 e identificar det...


Impact of the 2009-2014 economic crisis on suicide attempts and self-harm in Po...

Pinheiro, Vera; Nunes, Baltazar; Silva, Susana Pereira; Caetano, Constantino

Following the worldwide economic crisis of 2008, studies have found an increased risk for self-harm and suicide attempts, many of which need hospital care. There is no research in Portugal on the matter. Therefore, our goal was to estimate the impact of the Portuguese economic crisis of 2009-2014 on the hospital admission rates by attempted suicide and self-harm in Portugal.


SIDA à data do diagnóstico de infeção por VIH e por evolução de estádio (2009-2...

Cortes Martins, Helena; Caetano, Constantino; Aldir, Isabel

Introdução: A utilização de fármacos antirretrovirais altamente eficazes no controlo da infeção por VIH levou à redução da incidência de SIDA em Portugal, contudo esta mantém-se das mais elevadas da União Europeia. Objetivo: Comparar as características dos casos de SIDA concomitantes com o diagnóstico de infeção por VIH, com aqueles resultantes de evolução de estádio (diagnósticos diferidos), na última década. ...


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