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EBV infection and expression of HER2 and CD34 in gastric cancer, how are they r...

Mendes, Fernando; Pinheiro, Alexandra; Rocha, Clara; Melo, Fernando; Morais, Inês; Colaço, Inês; Andrade, Sara; Caetano, Rui; Carreira, Patrícia

Introduction: Gastric cancer (GC), as a multifactorial disease, exhibits a complex pathogenesis, having intra- and inter-tumor heterogeneity, challenging the efficacy of current treatments[1,2]. GC as a major global health problem, better diagnostic and therapeutic strategies are needed, leading to further biomarkers research associated to innovative targeted therapies[3,4]. Objectives: Our aim was to study hum...


Impact of Positive Surgical Margins After Partial Nephrectomy

Carvalho, João André Mendes; Nunes, Pedro; Silva, Edgar Tavares da; Parada, Belmiro; Jarimba, Roberto; Moreira, Pedro; Retroz, Edson; Caetano, Rui

Background: The impact of positive surgical margins (PSMs) after partial nephrectomy (PN) is controversial. Objective: To evaluate the risk factors for a PSM and its impact on overall survival. Design, setting, and participants: This is a retrospective study of 388 patients were submitted to PN between November 2005 and December 2016 in a single centre. Two groups were created: PSM and negative surgical margin ...


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