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Evidence for an association of prenatal exposure to particulate matter with cli...

Santos, João Xavier; Sampaio, Pedro; Rasga, Célia; Martiniano, Hugo; Faria, Clarissa; Café, Cátia; Oliveira, Alexandra; Duque, Frederico

Early-life exposure to air pollutants, including ozone (O3), particulate matter (PM2.5 or PM10, depending on diameter of particles), nitrogen dioxide (NO2) and sulfur dioxide (SO2) has been suggested to contribute to the etiology of Autism Spectrum Disorder (ASD). In this study, we used air quality monitoring data to examine whether mothers of children with ASD were exposed to high levels of air pollutants duri...


Prevalence of Autism Spectrum Disorder in the Centro region of Portugal: a popu...

Rasga, Célia; Santos, João Xavier; Café, Cátia; Oliveira, Alexandra; Duque, Frederico; Posada, Manuel; Nunes, Ana; Oliveira, Guiomar

Introduction: Accurate prevalence estimates for Autism Spectrum Disorder (ASD) are fundamental to adequately program medical and educational resources for children. However, estimates vary globally and across Europe, and it is therefore wise to conduct epidemiological studies in defined geo-cultural contexts. Methods: We used a population screening approach to estimate the prevalence of ASD in the Centro region...


Prevalence of autism spectrum disorder in the centro region of Portugal: A popu...

Rasga, Célia; Xavier Santos, João; Café, Cátia; Oliveira, Alexandra; Duque, F; Posada, Manuel; Nunes, Ana; Oliveira, Guiomar; Vicente, Astrid M

Introduction: Accurate prevalence estimates for Autism Spectrum Disorder (ASD) are fundamental to adequately program medical and educational resources for children. However, estimates vary globally and across Europe, and it is therefore wise to conduct epidemiological studies in defined geo-cultural contexts. Methods: We used a population screening approach to estimate the prevalence of ASD in the Centro region...


Evidence for an association of prenatal exposure to particulate matter with cli...

Xavier Santos, João; Sampaio, Pedro; Rasga, Célia; Martiniano, Hugo; Farias, Clarissa; Café, Cátia; Oliveira, Alexandra; Duque, F; Oliveira, Guiomar

Early-life exposure to air pollutants, including ozone (O3), particulate matter (PM2.5 or PM10, depending on diameter of particles), nitrogen dioxide (NO2) and sulfur dioxide (SO2) has been suggested to contribute to the etiology of Autism Spectrum Disorder (ASD). In this study, we used air quality monitoring data to examine whether mothers of children with ASD were exposed to high levels of air pollutants duri...


Prevalence of Autism Spectrum Disorder in the Centro region of Portugal: a popu...

Rasga, Célia; Santos, João Xavier; Café, Cátia; Oliveira, Alexandra; Duque, Frederico; Posada, Manuel; Nunes, Ana; Oliveira, Guiomar

Introduction: Accurate prevalence estimates for Autism Spectrum Disorder (ASD) are fundamental to adequately program medical and educational resources for children. However, estimates vary globally and across Europe, and it is therefore wise to conduct epidemiological studies in defined geo-cultural contexts. Methods: We used a population screening approach to estimate the prevalence of ASD in the Centro region...


Parahippocampal deactivation and hyperactivation of central executive, saliency...

Mouga, Susana; Duarte, Isabel Catarina; Café, Cátia; Sousa, Daniela; Duque, Frederico; Oliveira, Guiomar; Castelo-Branco, Miguel

The concomitant role of the Central Executive, the Saliency and the Social Cognition networks in autism spectrum disorder (ASD) in demanding ecological tasks remains unanswered. We addressed this question using a novel task-based fMRI virtual-reality task mimicking a challenging daily-life chore that may present some difficulties to individuals with ASD: the EcoSupermarketX.; This research was supported by the ...


Social Attention Deficits in Children With Autism Spectrum Disorder: Task Depen...

Mouga, Susana; Castelhano, João; Café, Cátia; Sousa, Daniela; Duque, Frederico; Oliveira, Guiomar; Castelo-Branco, Miguel

Social attention deficits represent a central impairment of patients suffering from autism spectrum disorder (ASD), but the nature of such deficits remains controversial. We compared visual attention regarding social (faces) vs. non-social stimuli (objects), in an ecological diagnostic context, in 46 children and adolescents divided in two groups: ASD (N = 23) and typical neurodevelopment (TD) (N = 23), matched...


Attentional Cueing and Executive Deficits Revealed by a Virtual Supermarket Tas...

Mouga, Susana; Duarte, Isabel Catarina; Café, Cátia; Sousa, Daniela; Duque, Frederico; Oliveira, Guiomar; Castelo-Branco, Miguel

Executive functioning (EF) impairments in Autism Spectrum Disorder (ASD) impact on complex functions, such as social cognition. We assessed this link between EF, attentional cueing, and social cognition with a novel ecological task, "EcoSupermarketX." Our task had three blocks of increasing executive load and incorporated social and non-social cues, with different degrees of saliency. Performance of ASD and typ...


Prevalência da perturbação do espectro do autismo na região Centro de Portugal:...

Rasga, Célia; Santos, João; Café, Cátia; Oliveira, Alexandra; Duque, Frederico; Nunes, Ana; Oliveira, Guiomar; Vicente, Astrid

A prevalência da perturbação do espectro do autismo (PEA) em crianças foi estimada na região Centro de Portugal, no âmbito do projeto Autism Spectrum Disorders in the European Union (ASDEU). A metodologia de estudo baseou-se no rastreio de crianças entre os 7 e 9 anos matricula- das, no ano letivo de 2016/2017, em escolas primárias desta região. O rastreio incluiu todas as escolas com unidades de apoio especial...


Prevalência da perturbação do espectro do autismo na região Centro de Portugal:...

Rasga, Célia; Santos, João Xavier; Café, Cátia; Oliveira, Alexandra; Duque, Frederico; Nunes, Ana; Oliveira, Guiomar; Vicente, Astrid Moura

A prevalência da perturbação do espectro do autismo (PEA) em crianças foi estimada na região Centro de Portugal, no âmbito do projeto Autism Spectrum Disorders in the European Union (ASDEU). A metodologia de estudo baseou-se no rastreio de crianças entre os 7 e 9 anos matriculadas, no ano letivo de 2016/2017, em escolas primárias desta região. O rastreio incluiu todas as escolas com unidades de apoio especializ...


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