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Urinary Biomarkers in Bladder Cancer: Where Do We Stand and Potential Role of E...

Castanheira De Oliveira, Manuel; Caires, Hugo R.; Oliveira, Maria J; Fraga, Avelino; Vasconcelos, M. Helena; Ribeiro, Ricardo

Extracellular vesicles (EVs) are small membrane vesicles released by all cells and involved in intercellular communication. Importantly, EVs cargo includes nucleic acids, lipids, and proteins constantly transferred between different cell types, contributing to autocrine and paracrine signaling. In recent years, they have been shown to play vital roles, not only in normal biological functions, but also in pathol...


Urinary biomarkers in bladder cancer : where do we stand and potential role of ...

Oliveira, Manuel Castanheira de; Caires, Hugo R.; Oliveira, Maria J.; Fraga, Avelino; Vasconcelos, M. Helena; Ribeiro, Ricardo

Extracellular vesicles (EVs) are small membrane vesicles released by all cells and involved in intercellular communication. Importantly, EVs cargo includes nucleic acids, lipids, and proteins constantly transferred between different cell types, contributing to autocrine and paracrine signaling. In recent years, they have been shown to play vital roles, not only in normal biological functions, but also in pathol...


Eucalyptus globulus Labill. decoction extract inhibits the growth of NCI-H460 c...

Teixeira, Alexandra Margarida; Dacunha, Déborah C.; Barros, Lillian; Caires, Hugo R.; Xavier, Cristina P.R.; Ferreira, Isabel C.F.R.

Eucalyptus globulus Labill. is a widespread evergreen plant belonging to the Myrtaceae family. Several species of Eucalyptus are known to have a plethora of medicinal properties, particularly anti-tumor activity, which prompts the study of the chemical composition and bioactivity of extracts from this plant. Hereby, the main aims of this work were to (i) profile the phenolic compounds in E. globulus extracts pr...

Date: 2019   |   Origin: Biblioteca Digital do IPB

Study of Non-Targeted Effects Induced on Cell Lines Using Low Doses of Ionizing...

Caires, Hugo R.; Costa, Pedro; Lemos, Joana; Silva, Regina; Bravo, Isabel; Cunha, Lídia; Metello, Luís F.

The LNT - Linear-no-Threshold model, used to analyze dose-effect ratios after biological irradiation exposures, theorizes that effects produced are directly proportional to the irradiating doses, with a linear without threshold pattern. Nevertheless, there is a relevant number of evidence, accumulated essentially over the last decade, suggesting that risks inherent to low doses of irradiation cannot be strictly...


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