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Different ability of multidrug-resistant and-sensitive counterpart cells to rel...
Sousa, D; Lima, RT; Lopes-Rodrigues, V; Gonzalez, E; Royo, F; Xavier, CPR; Falcón-Pérez, JM; Vasconcelos, MHCancer multidrug resistance (MDR) is one of the main challenges for cancer treatment efficacy. MDR is a phenomenon by which tumor cells become resistant to several unrelated drugs. Some studies have previously described the important role of extracellular vesicles (EVs) in the dissemination of a MDR phenotype. EVs’ cargo may include different players of MDR, such as microRNAS and drug-efflux pumps, which may be...
Date: 2021
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Origin: Repositório Aberto da Universidade do Porto