Funding Information: We would like to thank the previous and current members of S.T.d.R.’s team for helpful discussions. We also thank Felix Krueger, Maria Gouveia, Teresa Silva, Marta Furtado, and Adriana Vieira for technical help during the execution of this work. Work in S.T.d.R.’s team was supported by Fundação para a Ciência e a Tecnologia (FCT) Ministério da Ciência, Tecnologia e Ensino Superior (MCTES), ...
This work was supported by the Helmholtz Association (to A.P., S.G. and S.D.), by the Funda\u00E7ao\u0303 para a Ci\u00EAncia e Tecnologia (PD/BD/135453/2017 and COVID/BD/ 152489/2022 to S.C., UIDP/04378/2020, UIDB/04378/2020, LA/P/0140/2020 to A.R.G.), by the Deutsche Forschungsgemeinschaft (DFG; German Research Foundation) (International Research Training Group IRTG2403 to A.P. and L.Z.-R.), by the DFG under ...
We thank João Neto, Silvia Carvalho, and the remaining Computational Multi-Omics Lab members at UCIBIO for their helpful comments and suggestions. Paulo Caldas was a recipient of a Marie Skłodowska-Curie Postdoctoral Fellowship (FOX-MTN-HORIZON-MSCA - 2021-PF-01-01). This work was financed by national funds from Fundação para a Ciência e Tecnologia (FCT), in the scope of the projects UIDP/04378/2020 and UIDB/04...
Funding Information: We acknowledge members of the Loose laboratory at IST Austria for helpful discussions—in particular L. Lindorfer for his assistance with cloning and purifications. We thank J. Löwe and T. Nierhaus (MRC-LMB Cambridge, UK) for sharing unpublished work and helpful discussions, as well as D. Vavylonis and D. Rutkowski (Lehigh University, Bethlehem, PA, USA) and S. Martin (University of Lausanne...
Funding Information: ariana Ferreira, Marie Bordone, Nuno Agostinho and Nuno Barbosa Morais (Disease Transcriptomics Lab, iMM) for input on bioinformatics analysis. Pedro Papotto, Karine Serre (Immuno-Biology & Immuno-Oncology Lab, iMM), Idálio Viegas (Biology of Parasitism Lab, iMM), Isabel Alcobia (Institute of Histology and Developmental Biology, FMUL), Debanjan Mukherjee, Vanessa Zuzarte-Luís (Biology & Phy...
PTDC/BIA-MOL/30438/2017 PTDC/MED-OUT/4301/2020 RiboMed 857119 PD/BD/128292/2017 LCF/PR/HP21/52310016 PTDC/BIA-MOL/6624/2020 PTDC/MED-ONC/7864/2020; DNA oxidation by ten-eleven translocation (TET) family enzymes is essential for epigenetic reprogramming. The conversion of 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) initiates developmental and cell-type-specific transcriptional programs through mec...