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Determinants of HIV-1 Transmission Clusters and Transmitted Drug Resistance in ...

Abrantes, Ricardo; Pimentel, Victor; Sebastião, Cruz; Miranda, Mafalda N S; Seabra, Sofia; Silva, Ana Rita; Diniz, António; Ascenção, Bianca

Introduction: In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determina...


Determinants of HIV-1 transmission clusters and transmitted drug resistance in ...

Abrantes, Ricardo; Pimentel, Victor; Sebastião, Cruz; Miranda, Mafalda N. S.; Seabra, Sofia; Silva, Ana Rita; Diniz, António; Ascenção, Bianca

In the EU/EEA, men who have sex with men (MSM) is a priority group for the prevention and control of HIV-1 infection. In Portugal, the 2023 HIV incidence rate was 8.2 per 100,000 inhabitants, with 876 new infections, 41.7% in MSM. We aim to characterize HIV-1 transmission clusters (TC) and transmitted drug resistance (TDR) and its sociodemographic, behavioral, clinical, and viral genomic determinants in MSM new...


Determinants of HIV late presentation among men who have sex with men in Portug...

Abrantes, Ricardo; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca; Piñeiro, Carmela; Koch, Carmo

Introduction: HIV late presentation (LP) remains excessive in Europe. We aimed to analyze the factors associated with late presentation in the MSM population newly diagnosed with HIV in Portugal between 2014 and 2019. Methods: We included 391 newly HIV-1 diagnosed Men who have Sex with Men (MSM), from the BESTHOPE project, in 17 countrywide Portuguese hospitals. The data included clinical and socio-behavioral q...


Determinants of HIV late presentation among men who have sex with men in Portug...

Abrantes, Ricardo; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca; Piñeiro, Carmela; Koch, Carmo

Introduction HIV late presentation (LP) remains excessive in Europe. We aimed to analyze the factors associated with late presentation in the MSM population newly diagnosed with HIV in Portugal between 2014 and 2019.Methods We included 391 newly HIV-1 diagnosed Men who have Sex with Men (MSM), from the BESTHOPE project, in 17 countrywide Portuguese hospitals. The data included clinical and socio-behavioral ques...


HIV-1-Transmitted Drug Resistance and Transmission Clusters in Newly Diagnosed ...

Pingarilho, Marta; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca Branco; Piñeiro, Carmela; Koch, Carmo

Objective: To describe and analyze transmitted drug resistance (TDR) between 2014 and 2019 in newly infected patients with HIV-1 in Portugal and to characterize its transmission networks. Methods: Clinical, socioepidemiological, and risk behavior data were collected from 820 newly diagnosed patients in Portugal between September 2014 and December 2019. The sequences obtained from drug resistance testing were us...


HIV-1-transmitted drug resistance and transmission clusters in newly diagnosed ...

Pingarilho, Marta; Pimentel, Victor; Miranda, Mafalda N. S.; Silva, Ana Rita; Diniz, António; Ascenção, Bianca Branco; Piñeiro, Carmela; Koch, Carmo

Objective: To describe and analyze transmitted drug resistance (TDR) between 2014 and 2019 in newly infected patients with HIV-1 in Portugal and to characterize its transmission networks. Methods: Clinical, socioepidemiological, and risk behavior data were collected from 820 newly diagnosed patients in Portugal between September 2014 and December 2019. The sequences obtained from drug resistance testing were us...


O desafio diagnóstico de uma zoonose

Silva Pinto, Susana; Aires Pereira, Raquel; Graça, Ana Luísa; Caldas, Cátia; Sarmento, António

Introdução: A febre Q é uma zoonose, causada pela Coxiella burnetii. Esta bactéria está presente em produtos de animais, sobretudo gado ovino, caprino e bovino e transmite-se ao humano pela inalação de aerossóis. Sendo uma doença de declaração obrigatória em Portugal desde 1999, é epidemiologicamente relevante em todo o mundo, tanto na sua forma aguda, com relato de vários surtos na última década, como na sua f...


A case control study on the diagnostic potential of multiantigen serological te...

Duarte, Raquel; Afonso, Andrea; Ferreira, Carina; Roque, Susana; Vasconcelos, Olga; Castro, Rui Sarmento; Tavares, Margarida; Caldas, Cátia

Background: Eradicating tuberculosis (TB) in European countries with high incidence, such as Portugal, rely to a great extent on the ability to perform early accurate diagnosis. For the first time, the diagnostic value of two serologic tests, TB STAT-PAK II and MAPIA, was evaluated for rapid tuberculosis detection in a Portuguese cohort. Materials and Methods: A multicentre case-control study was performed on i...


Doenças Definidoras de SIDA - Experiência de três anos em um Serviço de Doenças...

Coelho, Rui; Cardoso, Sara; Poínhos, Rui; Piñeiro, Carmela; Caldas, Cátia; Soares, Jorge; Serrão, Rosário; Sarmento, António


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