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Anatomical factors in medication-related osteonecrosis of the jaws
Correia, J. A.; Lóio, A.; Furtado, I. A.; Capelo, A.; Caldas, C.; Santos, N.; Salvado, F.
Date: 2021
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Origin: Egas Moniz - Cooperativa de Ensino Superior, CRL
Genetic disruption of NRF2 promotes the development of necroinflammation and li...
Duarte, T.; Caldas, C.; Santos, A.; Silva-Gomes, S.; Santos-Gonçalves, A.; Martins, M.; Porto, G.; Lopes, J.In hereditary hemochromatosis, iron deposition in the liver parenchyma may lead to fibrosis, cirrhosis and hepatocellular carcinoma. Most cases are ascribed to a common mutation in the HFE gene, but the extent of clinical expression is greatly influenced by the combined action of yet unidentified genetic and/or environmental modifying factors. In mice, transcription factor NRF2 is a critical determinant of hepa...
Date: 2017
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Origin: Repositório Científico da Unidade Local de Saúde de Santo António (ULSSA)