Feminino, 57 anos, antecedentes de Hipertensão e Leiomioma uterino. Referenciada à consulta de Medicina Interna por anemia. Durante a primeira consulta, foram observadas várias lesões nodulares fibrosas e móveis, maioritariamente no tronco, abdómen e costas, com 2 manchas café-au-lait. Lesões semelhantes no pai e na tia paterna, sem diagnóstico. A Doente não apresentava alteração do crescimento nem do desenvol...
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Evolutionary responses may be crucial in allowing organisms to cope with prolonged effects of climate change. However, a clear understanding of the dynamics of adaptation to warming environments is still lacking. Addressing how reproductive success evolves in such deteriorating environments is extremely relevant, as this trait is constrained at temperatures below critical thermal limits. Experimental evolution ...
Acute coronary syndromes (ACS) are considered a continuum, enclosing both non-ST-elevation (NSTE)-ACS, including unstable angina and non-ST-elevation myocardial infarction (NSTEMI), and ST-elevation myocardial infarction (STEMI). The diagnosis of myocardial infarction (MI) is associated with troponin release. Classification of MI has fundamentally been based on the presence or absence of ST-segment elevation (S...
Este relatório é o culminar de dois anos do curso técnico superior profissional (TeSP) de “Manutenção e Reparação Automóvel” e nele irei descrever as atividades realizadas durante o estágio curricular, com duração de 750 horas, efetuado na “Finiclasse 2000 – Comércio e gestão de automóveis – Intermercados SA”. Durante este período tive a possibilidade de observar e realizar inúmeras operações de manutenção, dia...
Exposure to extreme temperatures can negatively affect animal reproduction, by disrupting the ability of individuals to produce any offspring (fertility), or the number of offspring produced by fertile individuals (fecundity). This has important ecological consequences, because reproduction is the ultimate measure of population fitness: a reduction in reproductive output lowers the population growth rate and in...
A comprehensive understanding of the genetic mechanisms that shape species responses to thermal variation is essential for more accurate predictions of the impacts of climate change on biodiversity. Experimental evolution with high-throughput resequencing approaches (evolve and resequence) is a highly effective tool that has been increasingly employed to elucidate the genetic basis of adaptation. The number of ...
Understanding the molecular mechanisms of thermal adaptation is crucial to predict the impacts of global warming. However, there is still a lack of research on the effects of rising temperatures over time and of studies involving different populations from the same species. The present study focuses on these two aspects, which are of great importance in understanding how organisms cope and adapt to ongoing chan...