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Maternal dietary exposure to mycotoxin aflatoxin B1 promotes intestinal immune ...

Bastos-Amador, Patricia; Duarte, Elsa Leclerc; Torres, Júlio; Caldeira, Ana Teresa; Silva, Inês; Salvador, Cátia; Assunção, Ricardo; Alvito, Paula

Abstract: Mycotoxins are secondary metabolites produced by fungi occurring in food that are toxic to animals and humans. Early-life mycotoxins exposure has been linked to diverse pathologies. However, how maternal exposure to mycotoxins impacts on the intestinal barrier function of progeny has not been explored. Here, exposure of pregnant and lactating C57Bl/6J female mice to aflatoxin B1 (AFB1; 400 μg/kg body ...


Biosynthesis of Metal and Metal Oxide Nanoparticles Using Microbial Cultures: M...

Carrapiço, António; Martins, Maria Rosário; Caldeira, Ana Teresa; Mirão, José; Dias, Luís

Nanoparticles (1 to 100 nm) have unique physical and chemical properties, which makes them suitable for application in a vast range of scientific and technological fields. In particular, metal nanoparticle (MNPs) research has been showing promising antimicrobial activities, paving the way for new applications. However, despite some research into their antimicrobial potential, the antimicrobial mechanisms are st...


Assessing aesthetic and structural deterioration in historic buildings – a cont...

Dias, Luís; Rosado, Tânia; Sriradha, Bhattacharya; Candeias, António; Caldeira, Ana Teresa; Mirão, José

An important part of our cultural heritage assets is built of natural stone since it has always been a material of excellence due to its inherent characteristics. Despite the physical and mechanical properties that give relatively long durability as a construction material, some characteristics are less durable, namely color or eventual surface finishes. The alteration of its aesthetic features may be followed ...


Maternal dietary exposure to mycotoxin aflatoxin B1 promotes intestinal immune ...

Bastos Amador, Patricia; Duarte, Elsa Leclerc; Caldeira, Ana Teresa; Salvador, Catia; Assunção, Ricardo; Alvito, Paula; Ferreira, Manuela; Silva, Ines

Mycotoxins are secondary metabolites produced by fungi occurring in food that are toxic to animals and humans. Early-life mycotoxins exposure has been linked to diverse pathologies. However, how maternal exposure to mycotoxins impacts on the intestinal barrier function of progeny has not been explored. Here, exposure of pregnant and lactating C57Bl/6J female mice to aflatoxin B1 (AFB1; 400 μg/kg body weight/day...


Insights on the second phase of the multidisciplinary study of the Viceroys por...

Reis, Teresa; Valadas, Sara; Machado, Ana; Piorro, Luís; Pereira, Fernando António Baptista; Caldeira, Ana Teresa; Vandenabeele, Peter

"Old Goa Revelations" is an international collaborative project dedicated to the research of a shared heritage collection associated to the Portuguese Presence in India (1505 – 1961). The upper halls of the Archaeological Survey of India (ASI) Museum in Old Goa, display the portrait gallery of these Viceroys and Governors who administrated these territories and used to commission their depictions before leaving...


Underneath the Purple Stain

Pinheiro, Catarina; Miller, Ana; Vaz, Patricia; Caldeira, Ana Teresa; Casanova, Conceição

The Alcobacenses are one of the most important Portuguese collections of Monastic codices. During a campaign study to further advance our knowledge on this important legacy and its state of conservation, a heavily deteriorated codex (ALC.338) stood out due to the presence of purple stains on the lower margins on virtually all folios. In some of them, the purple stains are accompanied by yellow and brown patches...


Unveiling the Effectiveness of Innovative Commercial Coatings Used for the Pres...

Dias, Luís; Nunes, Ricardo; Costa, Mafalda; Caldeira, Ana Teresa; Mirão, José; Barrulas, Pedro

The preservation of natural stone heritage is still a major challenge for the scientific community. This topic assumes a greater importance since it impacts economic and socio-cultural values. Recent research has indicated that water action and microorganism activity are among the major contributors to the deterioration of this material. Despite the emergence of new protective solutions in the market, some cons...


Chemical-physical agents and biodeteriogens in the alteration of limestones use...

Columbu, Stefano; Sitzia, Fabio; Bachetta, Gianluigi; Podda, Lina; Calvia, Giacomo; Coroneo, Valentina; Pirinu, Andrea; Josè, Mirao; Moita, Patricia

The alteration of rocks is usually due to the chemical-physical processes that are initially established on the outer surface of the stone and gradually proceed towards the inner matrix. The chemical alteration generated by the interaction with atmospheric agents (weathering) involves the transformation of the mineral phases constituting the rock that are less stable in the current climatic conditions. That oft...


Colored microbial coatings in show caves from the galapagos islands (Ecuador): ...

Miller, Ana Zélia; García-Sánchez, A.M.; Coutinho, M.L.; Pereira, M.F.C.; Gázquez, F.; Calaforra, J.M.; Forti, P.; Martínez-Frías, J.; Toulkeridis, T.

The Galapagos Islands (Ecuador) have a unique ecosystem on Earth due to their outstanding biodiversity and geological features. This also extends to their subterranean heritage, such as volcanic caves, with plenty of secondary mineral deposits, including coralloid-type speleothems and moonmilk deposits. In this study, the bacterial communities associated with speleothems from two lava tubes of Santa Cruz Island...


Plastic toy soldiers, a lost battle? – an analytical perspective

Pereira, António; Candeias, António; Cardoso, Ana; Mirão, José; Caldeira, Ana Teresa

The preservation and conservation of museum collections requires a detailed understanding of their constituent materials. The use of a wide variety of instrumental techniques can provide complementary data regarding the composition and structure of these materials. A set of plastic toy soldiers (mid 20th century) from the Oporto Military Museum (Museu Militar do Porto) exibited accelerated deterioration. To bet...

Data: 2021   |   Origem: Conservar Património

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