11 documents found, page 1 of 2
An Artificial Intelligence Approach to Thrombophilia Risk
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThrombophilia stands for a genetic or an acquired tendency to hypercoagulable states, frequently as venous thrombosis. Venous thromboembolism, represented mainly by deep venous thrombosis and pulmonary embolism, is often a chronic illness, associated with high morbidity and mortality. Therefore, it is crucial to identify the cause of the disease, the most appropriate treatment, the length of treatment or preven...
A Case Base View of Heart Failure Predisposition Risk
Vicente, Henrique; Martins, M. Rosário; Duarte, Margarida; Miguel, Patrícia; Grañeda, José M.; Caldeira, Filomena; Vilhena, João; Neves, JoãoHeart failure stands for an abnormality in cardiac structure or function which results in the incapability of the heart to deliver oxygen at an ideal rate. This is a worldwide problem of public health, characterized by high mortality, frequent hospitalization and reduced quality of life. Thus, this work will focus on the development of a decision support system to assess heart failure predisposing risk. The fra...
Cross-protection to new drifted influenza A(H3) viruses and prevalence of prote...
Guiomar, Raquel; Pereira da Silva, Susana; Conde, Patrícia; Cristóvão, Paula; Maia, Ana Carina; Pechirra, Pedro; Rodrigues, Ana Paula; Nunes, BaltazarIntroduction: Immune profile for influenza viruses is highly changeable over time. Serological studies can assess the prevalence of influenza, estimate the risk of infection, highlight asymptomatic infection rate and can also provide data on vaccine coverage. The aims of the study were to evaluate pre-existing cross-protection against influenza A(H3) drift viruses and to assess influenza immunity in the Portugu...
An Integrated Soft Computing Approach to Hughes Syndrome Risk Assessment
Vilhena, João; Martins, M. Rosário; Vicente, Henrique; Grañeda, José M.; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThe AntiPhospholipid Syndrome (APS) is an acquired autoimmune disorder induced by high levels of antiphospholipid antibodies that cause arterial and veins thrombosis, as well as pregnancy-related complications and morbidity, as clinical manifestations. This autoimmune hypercoagulable state, usually known as Hughes syndrome, has severe consequences for the patients, being one of the main causes of thrombotic dis...
An Artificial Intelligence Approach to Thrombophilia Risk
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José M.; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThrombophilia stands for a genetic or an acquired tendency to hypercoagulable states, frequently as venous thrombosis. Venous thromboembolism, represented mainly by deep venous thrombosis and pulmonary embolism, is often a chronic illness, associated with high morbidity and mortality. Therefore, it is crucial to identify the cause of the disease, the most appropriate treatment, the length of treatment or preven...
Cross-protection to new drifted influenza A(H3) viruses and prevalence of prote...
Guiomar, Raquel; Pereira da Silva, Susana; Conde, Patrícia; Cristóvão, Paula; Maia, Ana Carina; Pechirra, Pedro; Rodrigues, Ana Paula; Nunes, BaltazarIntroduction: Immune profile for influenza viruses is highly changeable over time. Serological studies can assess the prevalence of influenza, estimate the risk of infection, highlight asymptomatic infection rate and can also provide data on vaccine coverage. The aims of the study were to evaluate pre-existing cross-protection against influenza A(H3) drift viruses and to assess influenza immunity in the Portugu...
Antiphospholipid Syndrome Risk Evaluation
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José M.; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThe antiphospholipid syndrome is an acquired autoimmune disorder produced by high titers of antiphospholipid antibodies that cause both arterial and veins thrombosis as well as pregnancy-related complications and morbidity, as clinical manifestations. This autoimmune hypercoagulable state, often associated with coronary artery disease and recurrent Acute Myocardium Infraction, has severe consequences for the pa...
A case-based reasoning view of thrombophilia risk
Vilhena, João; Vicente, Henrique; Martins, M. Rosário; Grañeda, José; Caldeira, Filomena; Gusmão, Rodrigo; Neves, João; Neves, JoséThrombophilia stands for a genetic or an acquired tendency to hypercoagulable states that increase the risk of venous and arterial thromboses. Indeed, venous thromboembolism is often a chronic illness, mainly in deep venous thrombosis and pulmonary embolism, requiring lifelong prevention strategies. Therefore, it is crucial to identify the cause of the disease, the most appropriate treatment, the length of trea...
Influenza seroprotection correlates with predominant circulating viruses during...
Guiomar, Raquel; Cristóvão, Paula; Conde, Patrícia; Costa, Inês; Pechirra, Pedro; Rodrigues, Ana Paula; Pereira da Silva, Susana; Nunes, BaltazarBACKGROUND: Population immune profile for influenza is highly affected by circulating influenza viruses, thus changing the risk of infection for influenza. This study aims to assess influenza immunity in the Portuguese population by age groups, during 2014 and 2015 and establish a relationship between seroprotection and circulating influenza viruses in 2014/15 and 2015/16 seasons. METHODS: Two cross-sectional s...
Severe acute respiratory infections in the 2012/2013 season studied by the Port...
Guiomar, Raquel; Pechirra, Pedro; Conde, Patrícia; Cristóvão, Paula; Silvestre, Maria José; Almeida Santos, Madalena; Sobrinho Simões, JoanaDuring the 2009/10 influenza pandemic, a network of 14 laboratories located in the main reference hospitals from Portugal mainland, Madeira and Azores was established for the diagnosis of the new influenza A(H1N1)2009 pandemic strain. Since then, the network performs laboratory diagnosis of influenza as well as other respiratory pathogens, thus contributing to the laboratory diagnosis of respiratory disease in ...