27 documents found, page 1 of 3

MMPs at Work

Matrix metallopeptidases (MMPs) are enzymes that, in balance with their inhibitors, play a vital role in extracellular matrix remodelling, particularly during orthodontic tooth movement (OTM). Despite growing interest, significant research is still required to fully comprehend the mechanisms and signalling pathways involved in periodontal ligament remodelling and OTM, particularly those mediated by MMPs. This r...

In vitro evaluation of surface roughness and color variation after two brushing...

The aim was to evaluate the effect of different whitening toothpastes on the enamel surface roughness and color variation. Twenty-four molars were sectioned and divided into eight groups (n = 3) considering the following two factors under study: toothpaste type (Colgate® Total Original, Oral B® 3D White Luxe Perfection, Curaprox® Black is White, and Signal® White Now) and brushing protocol (short- and long-term...

Acanthosis Nigricans revisited

Acanthosis nigricans is a dermatosis, often described as a paraneoplastic syndrome or as a manifestation of insulin resistance. It occurs rarely and the clinician seldom sees it. The authors present a review of this cutaneous finding, as a means of increasing clinician awareness of this rare entity.; A acanthosis nigricans é uma dermatose referida frequentemente como síndroma paraneoplásica ou manifestação de í...

Restorative materials without Bis-GMA – myth or reality?

Effect of saccharomycin, a natural Saccharomyces cerevisiae biocide, on Hanseni...

Polymerizable matrix metalloproteinases’ inhibitors with potential application ...

Collagen cleavage by matrix metalloproteinase (MMP) is considered a major cause of dental resins long term failure. Most MMP inhibitors display significant toxicity and are unsuitable for dental resins’ applications. Here we report a study of a new class of inhibitors that display the unique property of being co-polymerizable with other vinyl compounds present in commercial dental resins, limiting their release...

Effect of saccharomycin, a natural Saccharomyces cerevisiae biocide, on Hanseni...

ABSTRACT: During spontaneous wine fermentations, most of the non-Saccharomyces yeasts present in grape musts show an early decline in their population. It was traditionally assumed that Saccharomyces cerevisiae (S.c.) prevalence was due to the higher resistance of this species to ethanol. However, wine fermentations performed with single cultures of non-Saccharomyces strains showed that those strains could with...

Varying the polishing protocol influences the color stability and surface rough...

Surface properties of composites such as roughness and color impact periodontal health and aesthetic outcomes. Novel bulk-fill composites with improved functionality are being introduced and, in light of the existing variety of finishing/polishing procedures, research of their surface properties is warranted. Sixty discs were prepared from bulk-fill composites (Filtek™ Bulk Fill Posterior Restorative and Fill-U...

Challenges in matrix metalloproteinases inhibition

Matrix metalloproteinases are enzymes that degrade the extracellular matrix. They have different substrates but similar structural organization. Matrix metalloproteinases are involved in many physiological and pathological processes and there is a need to develop inhibitors for these enzymes in order to modulate the degradation of the extracellular matrix (ECM). There exist two classes of inhibitors: endogenous...

Challenges in matrix metalloproteinases inhibition

Matrix metalloproteinases are enzymes that degrade the extracellular matrix. They have different substrates but similar structural organization. Matrix metalloproteinases are involved in many physiological and pathological processes and there is a need to develop inhibitors for these enzymes in order to modulate the degradation of the extracellular matrix (ECM). There exist two classes of inhibitors: endogenous...