Clostridioides difficile is an opportunistic pathogen that can cause a range of conditions, from asymptomatic carriage to severe illness, posing a significant public health threat due to its high mortality rates and substantial healthcare costs. Traditional treatment options, including antibiotics, often fail to eradicate the infection, leading to recurrent cases that severely impact patients’ lives. Intestinal...
Funding Information: This study was sponsored by Farmodi\u00E9tica S.A, a company operating in the field of nutritional and health products. The study was also promoted by the CINTESIS@RISE, NOVA Medical School, NOVA University of Lisbon, and funded by national funds through FCT\u2014Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia, I.P., under the project RISE\u2014LA/P/0053/2020. Farmodi\u00E9tica S.A. h...
Clostridioides difficile is an opportunistic pathogen that can cause a range of conditions, from asymptomatic carriage to severe illness, posing a significant public health threat due to its high mortality rates and substantial healthcare costs. Traditional treatment options, including antibiotics, often fail to eradicate the infection, leading to recurrent cases that severely impact patients' lives. Intestinal...
Funding Information: This work was sponsored by Farmodietica S.A. The study was also promoted by the CINTESIS@RISE, NOVA Medical School, NOVA University of Lisbon and financed by national funds through FCT Fundacao para a Ciencia e a Technologia, I.P., within the scope of the project \u201CRISE \u2013 LA/P/0053/2020\u201D. The sponsor and funder had no role in the study design and had no role during its executi...
Funding Information: CINTESIS\u2014UIDB/04255/2020 and UIDP/04255/2020, a program financially supported by Funda\u00E7\u00E3o para a Ci\u00EAncia e Tecnologia/Minist\u00E9rio da Ci\u00EAncia, Tecnologia e Ensino Superior, through national funds is acknowledged. Publisher Copyright: © 2024 by the authors.; The COVID-19 pandemic lockdowns affected the lifestyles of children and adolescents, leading to an increase...
Publisher Copyright: Copyright © 2024 Vilhais, Alpuim Costa, Fontes-Sousa, Ribeiro, Martinho, Botelho de Sousa, Santos, Negreiros, Canastra, Borralho, Guia Pereira, Marçal, Germano Sousa, Chaleira, Rocha, Calhau and Faria.; Locally advanced breast cancer poses significant challenges to the multidisciplinary team, in particular with hormone receptor (HR) positive, HER2-negative tumors that classically yield lowe...
Funding Information: Supported by ERDF through the operation POCI-01-0145-ERDF-007746 funded by the Programa Operacional Competitividade e Internacionaliza\u00E7\u00E3o \u2013 COMPETE2020 and by FCT - Funda\u00E7\u00E3o para a Ci\u00EAncia e a Tecnologia, IP national support through CINTESIS, R&D Unit (UIDB/4255/2020), CHRC (UIDP/04923/2020 and UIDB/04923/2020), and through the projects PTDC/BAA-AGR/7419/2020, ...
Locally advanced breast cancer poses significant challenges to the multidisciplinary team, in particular with hormone receptor (HR) positive, HER2-negative tumors that classically yield lower pathological complete responses with chemotherapy. The increasingly significant use of CDK 4/6 inhibitors (CDK4/6i) plus endocrine therapy (ET) in different breast cancer settings has led to clinical trials focusing on thi...
Blueberry extracts have been widely recognized as possessing antimicrobial activity against several potential pathogens. However, the contextualization of the interaction of these extracts with beneficial bacteria (i.e., probiotics), particularly when considering the food applications of these products, may be of importance, not only because their presence is important in the regular gut microbiota, but also be...