Made available in DSpace on 2022-04-29T08:29:59Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-02; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The presence of microbial biofilms in the wounds affects negatively the healing process and can contribute to therapeutic failures. This study aimed to establish the effective parameters of cold atmospheric plasma (CAP) against wound-...
The flatworm Schistosoma mansoni is a blood fluke parasite that causes schistosomiasis, a debilitating disease that occurs throughout the developing world. Current schistosomiasis control strategies are mainly based on chemotherapy, but many researchers believe that the best long-termstrategy to control schistosomiasis is through immunization with an antischistosomiasis vaccine combined with drug treatment. In ...
Qualitative and quantitative aspects of the superficial and profound cardiac plexus of dogs experimentally infected with Be-62 and Be-78 strains of Trypanosoma cruzi were studied. Animals were autopsied in the acute phase o f infection. The inflammatory process, lesions and number of parasites were more intense and frequent in animals infected with the Be-78 strain than in those infected with Be-62. Despite thi...
De acordo com os trabalhos publicados ate o momento, o cão esta sendo considerado, com ressalvas, como modelo ideal para o estudo da fase aguda e crônica indeterminada da tripanossomiase cruz jl 2 3 4 5 6 7 14 15 18 19 20 21 24 Os requisitos para um modelo ideal, estabelecidos pelo Comite de Doenca de Chagas do Programa Especial de Treinamento e Pesquisa de Doenças Parasitarias da Organização Mundial de Saude25...
Andrade caracterizou bem a fase aguda e a forma indeterminada da cardiopatia chagásica no cão1. Lana inoculando a cepa Be78 em cães caracterizou muito bem a cardiopatia chagásica crônica fibrosame, com quadro clínico e eletrocardiográfico muito semelhante a forma cardíaca humana". Pelo que sabemos, até o momento, não se documentou claramente a forma digestiva (megaesôfago e megacólon) experimental. Também não s...
Lesions observed in chronic chagasic cardiopathy frequently produce electrocardiographic alterations and affect cardiac function. Through a computerized morphometrical analysis we quantified the areas occupied by cardiac muscle, connective and adipose tissues in the right atrium of dogs experimentally infected with Trypanosoma cruzi. All of the infected dogs showed chronic myocarditis with variable reduction le...
Neste trabalho foi avaliada a influência da fonte do inóculo (tripomastigota sangüíneo ou metacíclico) e da via de inoculação (intraperitoneal ou conjuntival) na evolução da infecção de cães pelas cepas Berenice- 62 e Berenice-78 do Trypanosoma cruzi. O índice de infectividade e os níveis de parasitaemia foram significativamente influenciados pelas condições de inoculação, tendo sido maiores nos animais inocula...
When infected with Trypanosoma cruzi, Beagle dogs develop symptoms similar to those of Chagas disease in human beings, and could be an important experimental model for a better understanding of the immunopathogenic mechanisms involved in chronic chagasic infection. This study evaluates IL-10, IFN-g and TNF-a production in the sera, culture supernatant, heart and cervical lymph nodes and their correlation with c...