Made available in DSpace on 2022-04-29T07:20:29Z (GMT). No. of bitstreams: 0 Previous issue date: 1989-01-01; In this investigation the pathogenicity and immunogenicity of seven isolates of Paracoccidioides brasiliensis were compared. The pathogenicity of each isolate was determined by 50% lethal dose estimations and histopathology analysed during a 24-week-period. Four basic patterns of virulence could be defi...
Made available in DSpace on 2022-04-29T08:42:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2000-01-01; Most of our knowledge concerning the virulence determinants of pathogenic fungi comes from the infected host, mainly from animal models and more recently from in vitro studies with cell cultures. The fungi usually present intra- and/or extracellular host-parasite interfaces, with the parasitism phenomen...