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Curcumin-cinnamaldehyde hybrids as antiproliferative agents against women’s can...
Anselmo, Daiane B. [UNESP]; Polaquini, Carlos R. [UNESP]; Marques, Beatriz C. [UNESP]; Ayusso, Gabriela M. [UNESP]; Assis, Letícia R. [UNESP]Made available in DSpace on 2022-05-01T08:44:43Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; Curcumin and cinnamaldehyde are natural products whose antineoplastic activity has been well explored in biological evaluations. However, their poor chemical stability under physiological conditions has been an obstacle to their use as therapeutic agents. Herein, we designed and synthesized two series o...
Postnatal exposure to finasteride causes different effects on the prostate of m...
Maldarine, Juliana S.; Sanches, Bruno D. A.; Santos, Vitória A. [UNESP]; Cabral, Ágata S. [UNESP]; Lima, Maria L. D. [UNESP]Made available in DSpace on 2020-12-12T01:59:39Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-06-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The development and maintenance of prostate function depend on a fine balance between oestrogen and androgen levels. Finasteride inhibits 5α-reductase, which is responsibl...
Prenatal exposure to finasteride promotes sex-specific changes in gerbil prosta...
Maldarine, Juliana S.; Sanches, Bruno D. A.; Cabral, Ágata S. [UNESP]; Lima, Maria L. D. [UNESP]; Guerra, Luiz H. A. [UNESP]Made available in DSpace on 2019-10-06T16:38:10Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01; Finasteride is a drug that is widely used in the treatment of benign prostatic hyperplasia, hair loss and even as a chemotherapeutic agent in the treatment of prostatic adenocarcinoma. However, its use is known to cause several side effects in adults and it can also cause changes in the embryonic develo...