Parkinson's disease (PD) is the second most common neurodegenerative disorder being characterized by dopaminergic depletion in the nigrostriatal pathway. The pharmacological treatment of PD is palliative care, besides presenting a disabling adverse reaction profile. Neuroinflammation and oxidative stress (OE) are involved in the pathophysiology of PD and are important targets for treatments through neuroprotect...
This study performed a research about the use of medicinal plants in Picos city, identifying the plants grown in the garden belonging to the Laboratory of Phytotherapics in Picos (LAFIPI) and analying the use of phytotherapics distributed by the Farmácia Viva Project between 2008-2010. From the total of 750 interviewed participants, 37.6% were men and 62.4 % women. Most of them do not have secondary education (...
This study described the use of household insecticides in Picos (Piauí, Brazil), identify which are the most used types of insecticides and describes the incidence of poisoning and environmental awareness of the population. After home visits (n = 700), it was seen that the majority of respondents was represented by women (75%), with 31-55 years-old (49%), incomplete primary education (38.1%) and income between ...
In Brazil, intoxications by toxic plants are a public health problem, and difficulty in the identification of these species is the main cause of the problem. Hardly ever people know about the toxic potential of plant species, so the objective of this study was evaluate the popular knowledge in Francisco Santos - PI about toxic plants. 101 forms were randomly applied to the residents of the town, which were prev...
This article aims at reviewing the cytoprotective activity of extracts and active principles obtained from Maytenus ilicifolia and Maytenus aquifolium that have medicinal properties on gastric problems by inhibiting the hydrochloric acid secretion. Among the bioactive compounds of Maytenus ilicifolia, which may have antiulcerogenic action, we highlight the triterpenes, tannins and flavonoids. Studies with the s...
The teaching in health sciences has undergone important changes in recent years. In Brazil, courses such as medicine and nursing have suffered deep modifications in their educational projects of course (PPC) aiming at, generally speaking, the development of skills for greater ability to reason critically. The Pharmacology and Toxicology have highlighted importance in vocational training, because the medicines a...
The terpens centipedic acid (CA) and lactone of hawtriwaic acid (LAH) isolated from the flowers chapters of Egletes viscosa Less, popularly known as macela or macela da terra, were evaluated on 13-acetate-12-o-tetradecanoil-forbol (TPA) induced irritative contact dermatitis model and on oxazolone induced allergic contact dermatitis in mice. The centipedic acid and LAH on the following dosage of 0,125; 0,25 and ...