2 documents found, page 1 of 1
Rhinitis associated with asthma is distinct from rhinitis alone
Bousquet, J; Melén, E; Haahtela, T; Koppelman, G H; Togias, A; Valenta, R; Akdis, C A; Czarlewski, W; Rothenberg, M; Valiulis, A; Wickmann, M; Bonini, MAsthma, rhinitis and atopic dermatitis (AD) are interrelated clinical phenotypes that partly overlap in the human interactome. The concept of "one-airway-one-disease", coined over 20 years ago, is a simplistic approach of the links between upper- and lower-airway allergic diseases. With new data, it is time to reassess the concept. This article reviews (i) the clinical observations that led to Allergic Rhinitis...
European survey on national training activities in clinical research
Magnin, A; Iversen, V Cabral; Calvo, G; Čečetková, B; Dale, O; Demlova, R; Blasko, Gy; Keane, F; Kovacs, G L; Levy-Marchal, C; Monteiro, E.C.BACKGROUND: Investigator-initiated clinical studies (IITs) are crucial to generate reliable evidence that answers questions of day-to-day clinical practice. Many challenges make IITs a complex endeavour, for example, IITs often need to be multinational in order to recruit a sufficient number of patients. Recent studies highlighted that well-trained study personnel are a major factor to conduct such complex IITs...