6 documents found, page 1 of 1
Brazilian guidelines for the clinical management of paracoccidioidomycosis
Shikanai-Yasuda,Maria Aparecida; Mendes,Rinaldo Pôncio; Colombo,Arnaldo Lopes; Queiroz-Telles,Flávio de; Kono,Adriana Satie GonçalvesAbstract Paracoccidioidomycosis is a systemic fungal disease occurring in Latin America that is associated with rural environments and agricultural activities. However, the incidence and prevalence of paracoccidiodomycosis is underestimated because of the lack of compulsory notification. If paracoccidiodomycosis is not diagnosed and treated early and adequately, the endemic fungal infection could result in seri...
Terpinen-4-ol, tyrosol, and β-lapachone as potential antifungals against dimorp...
Brilhante,Raimunda Sâmia Nogueira; Caetano,Érica Pacheco; Lima,Rita Amanda Chaves de; Marques,Francisca Jakelyne de FariasAbstract This study aimed to evaluate the in vitro antifungal activity of terpinen-4-ol, tyrosol, and β-lapachone against strains of Coccidioides posadasii in filamentous phase (n = 22) and Histoplasma capsulatum in both filamentous (n = 40) and yeast phases (n = 13), using the broth dilution methods as described by the Clinical and Laboratory Standards Institute, to determine the minimum inhibitory concentrati...
Antiretroviral drugs saquinavir and ritonavir reduce inhibitory concentration v...
Brilhante,Raimunda Sâmia Nogueira; Caetano,Érica Pacheco; Riello,Giovanna Barbosa; Guedes,Glaucia Morgana de MeloAbstract Recent studies have shown that some drugs that are not routinely used to treat fungal infections have antifungal activity, such as protease inhibitor antiretroviral drugs. This study investigated the in vitro susceptibility of Histoplasma capsulatum var. capsulatum to saquinavir and ritonavir, and its combination with the antifungal itraconazole. The susceptibility assay was performed according to Clin...
Trichosporon species isolated from the perigenital region, urine and catheters ...
Silvestre Junior,Agenor Messias; Miranda,Mauricio Alexandre Bandeira Rampazzo; Camargo,Zoilo Pires deThe present study aimed to 1) determine the colonization rates of medically important Trichosporon species on normal perigenital skin and 2) determine the isolation rates of Trichosporon spp. isolated from the urine and catheters of Brazilian patients hospitalized in the Intensive Care Unit (ICU). The overall colonization rate of Trichosporon spp. was 11.15% (112 isolates). The most common species isolated from...
Natural antibodies in paracoccidioidomycosis
Unterkircher,Carmelinda S.; Leão,Mariella V.P.; Blotta,Maria Heloisa S.L.; Camargo,Zoilo Pires deRecent attention has been focused on the natural antibodies as a component of natural immunity and as integral part of the idiotypic network. However, their functional role in different infections has rarely been studied. This work was undertaken to investigate the presence of natural antibodies in paracoccidioidomycosis (PCM). In addition, we analyzed anti-P. brasiliensis antibodies and their distribution in I...
Paracoccidioidomicose em índios brasileiros da tribo Suruí: estudo clínico-labo...
Forjaz,Marly H.H.; Fischman,Olga; Camargo,Zoilo Pires de; Vieira Filho,João Paulo Botelho; Colombo,Arnaldo LopesParacoccidioidomicose é considerada a micose sistêmica endêmica mais prevalente na América Latina. Apesar da maior parte da casuística de paracoccidioidomicose ocorrer entre trabalhadores rurais, há poucos casos documentados de ocorrência dessa micose entre índios brasileiros. São apresentados 2 casos de paracoccidioidomicose em índios Suruí, família linguística Tupi-Mondé, procedentes de Cacoal, Rondônia. Ambo...