11 documents found, page 1 of 2
Increased apoptosis and decreased p53 and Bax expression in colorectal tumours
Borralho, PM; Ravasco, P; da Silva, IBM; Castro, RE; Ramalho, RM; Sola, S; Correia, L; Fernandes, A; Camilo, ME; Rodrigues, CMP
5,10-methylenetetrahydrofolate reductase (MTHFR) 677C - T and 1298A - C mutatio...
Castro, R; Rivera, I; Ravasco, P; Camilo, ME; Jakobs, C; Blom, HJ; de Almeida, IT
Enhanced apoptosis and Bcl-2 protein production in the liver of patients with s...
Ramalho, RM; Cortez-Pinto, H; Sola, S; Castro, RE; Camilo, ME; Moura, MC; Rodrigues, CMP
Hepatocyte apoptosis, expression of death receptors, and activation of NF-kappa...
Ribeiro, PS; Cortez-Pinto, H; Sola, S; Castro, RE; Ramalho, RM; Baptista, A; Moura, MC; Camilo, ME; Rodrigues, CMPOBJECTIVES: The increasing incidence of nonalcoholic (NASH) and alcoholic steatohepatitis (ASH), associated with lack of effective treatment, has prompted intensive studies on disease pathogenesis. Apoptosis is recognized as common in liver injury and may
Increased, homocysteine and S-adenosylhomocysteine concentrations and DNA hypom...
Castro, R; Rivera, I; Struys, EA; Jansen, EEW; Ravasco, P; Camilo, ME; Blom, HJ; Jakobs, C; de Almeida, ITBackground: The pathogenic mechanism of homocysteine's effect on cardiovascular risk is poorly understood. Recent studies show that DNA hypomethylation induced by increases in S-adenosylhomocysteine (AdoHcy), an intermediate of Hcy metabolism and a potent
Association between hepatocellular apoptosis and inflammation in patients with ...
Ribeiro, PS; Cortez-Pinto, H; Sola, S; Castro, RE; Baptista, A; Camilo, ME; Moura, MC; Rodrigues, CMP
5,10-Methylenetetrahydrofolate reductase 677C - T and 1298A - C mutations are g...
Castro, R; Rivera, I; Ravasco, P; Jakobs, C; Blom, HJ; Camilo, ME; de Almeida, ITBackground: Methylenetetrahydrofolate reductase (MTHFR) is one of the main regulatory enzymes of homocysteine metabolism. Elevated plasma total homocysteine (tHcy) is a major risk for cardiovascular disease. A common 677C--T mutation in the MTHFR gene re
Plasma total and free fatty acids composition in human non-alcoholic steatohepa...
De Almeida, IT; Cortez-Pinto, H; Fidalgo, G; Rodrigues, D; Camilo, MEBackground and aim: Non-alcoholic steatohepatitis (NASH), the association of steatosis with an inflammatory response, is a novel liver disease of unknown pathogenesis and prognosis. Triacylglycerols and their precursors, the fatty acids, are the likely ca
Apoptosis is a prominent feature of human alcoholic and non-alcoholic steatohep...
Rodrigues, CM; Cortez-Pinto, H; Sola, S; Filipe, P; Baptista, A; Camilo, ME; De Moura, MC
Increased free fatty acids in liver homogenate and mitochondria of ob/ob mice a...
de Almeida, IT; Rodrigues, D; Cortez-Pinto, H; Tenreiro, AM; Esteves, T; Camilo, ME