3 documents found, page 1 of 1
Mayaro virus induction of oxidative stress is associated with liver pathology i...
Caetano, Camila Carla da Silva; Camini, Fernanda Caetano; Almeida, Letícia Trindade; Ferraz, Ariane Coelho; Silva, Tales Fernando daMayaro virus (MAYV) causes Mayaro fever in humans, a self-limiting acute disease, with persistent arthralgia and arthritis. Although MAYV has a remerging potential, its pathogenic mechanisms remain unclear. Here, we characterized a model of MAYV infection in 3–4-week BALB/c mice. We investigated whether the liver acts as a site of viral replication and if the infection could cause histopathological alterations ...
Avaliação do estresse oxidativo e defesas antioxidantes após infecção pelo Maya...
Camini, Fernanda CaetanoPrograma de Pós-Graduação em Ciências Biológicas. Núcleo de Pesquisas em Ciências Biológicas, Pró-Reitoria de Pesquisa de Pós Graduação, Universidade Federal de Ouro Preto.; O Mayaro virus (MAYV) é um arbovírus negligenciado, de caráter emergente, que causa em humanos uma síndrome febril, a febre Mayaro, muitas vezes acompanhada por um quadro de artrite/artralgia incapacitante. Apesar de a febre Mayaro ser conh...
Oxidative stress in Mayaro virus infection.
Camini, Fernanda Caetano; Caetano, Camila Carla da Silva; Almeida, Letícia Trindade; Guerra, Joyce Ferreira da Costa; Silva, Breno de MelloMayaro virus (MAYV) is a neglected tropical arbovirus that causes a febrile syndrome that is sometimes accompanied by incapacitating arthritis/arthralgia. The pathogenesis of MAYV has not been completely defined and oxidative stress mediated by an increase in reactive oxygen species (ROS) and/or depletion of antioxidant defences has been found to contribute to several aspects of viral disease. To investigate wh...