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Glycans as key checkpoints of T cell activity and function

Pereira, MS; Alves, I; Vicente, M; Campar, A; Silva, MC; Padrão, NA; Pinto, V; Fernandes, Â; Dias, AM; Pinho, SS

The immune system is highly controlled and fine-tuned by glycosylation, through the addition of a diversity of carbohydrates structures (glycans) to virtually all immune cell receptors. Despite a relative backlog in understanding the importance of glycans in the immune system, due to its inherent complexity, remarkable findings have been highlighting the essential contributions of glycosylation in the regulatio...

Date: 2018   |   Origin: Repositório Aberto da Universidade do Porto
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