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Acute MDPV Binge Paradigm on Mice Emotional Behavior and Glial Signature
Campeão, Mafalda; Fernandes, Luciana; Pita, Inês R.; Lemos, Cristina; Ali, Syed F.; Carvalho, Félix; Rodrigues-Santos, Paulo; Ribeiro, Carlos A. Fontes3,4-Methylenedioxypyrovalerone (MDPV), a widely available synthetic cathinone, is a popular substitute for classical controlled drugs of abuse, such as methamphetamine (METH). Although MDPV poses public health risks, its neuropharmacological profile remains poorly explored. This study aimed to provide evidence on that direction. Accordingly, C57BL/6J mice were exposed to a binge MDPV or METH regimen (four intra...
Date: 2021
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Origin: Estudo Geral - Universidade de Coimbra