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Validation of a yellow fever vaccine model using data from primary vaccination ...

Bonin, Carla Rezende Barbosa; Fernandes, Guilherme Côrtes; Martins, Reinaldo de Menezes; Camacho, Luiz Antonio Bastos; Carvalho, Andréa Teixeira

Background: An effective yellow fever (YF) vaccine has been available since 1937. Nevertheless, questions regarding its use remain poorly understood, such as the ideal dose to confer immunity against the disease, the need for a booster dose, the optimal immunisation schedule for immunocompetent, immunosuppressed, and pediatric populations, among other issues. This work aims to demonstrate that computational too...

Date: 2021   |   Origin: Oasisbr

Analysis of the immunological biomarker profile during acute zika virus infecti...

Naveca, Felipe Gomes; Pontes, Gemilson Soares; Chang, Aileen Yu Hen; Silva, George Allan Villarouco da; Nascimento, Valdinete Alves do

BACKGROUND Infection with Zika virus (ZIKV) manifests in a broad spectrum of disease ranging from mild illness to severe neurological complications and little is known about Zika immunopathogenesis. OBJECTIVES To define the immunologic biomarkers that correlate with acute ZIKV infection. METHODS We characterized the levels of circulating cytokines, chemokines, and growth factors in 54 infected patients of both ...

Date: 2020   |   Origin: Oasisbr

IFN-? as a time-sensitive biomarker during Oropouche virus infection in early a...

Oliveira, Euz?bio de; Azevedo, Raimunda do Socorro Silva; Coelho-dos-Reis, Jordana Grazziela; Antonelli, Lis Ribeiro do Valle; Ferreira, Milene Silveira

Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.; Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.; Universidade Federal de Minas Gerais. Belo Horizonte, MG, Brazil / Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brazil.; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizon...

Date: 2019   |   Origin: Oasisbr

17DD Yellow Fever revaccination and heightened long-term immunity in population...

Campi-Azevedo, Ana Carolina; Peruhype-Magalh?es, Vanessa; Coelho-dos-Reis, Jordana Grazziela; Antonelli, Lis Ribeiro; Costa-Pereira, Christiane

Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais, Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior, Bio-Manguinhos/FIOCRUZ, PROEP/ CPqRR/FIOCRUZ, Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico?CNPq (grant nos. 444417/2014-1 and 458134/2014-7), and Programa Nacional de Imuniza??es, Secretaria de Vigil?ncia em Sa?de?Minist?rio da Sa?de, Brazil (grant no. TC 277/2013). O.A.M.-F., A...

Date: 2019   |   Origin: Oasisbr

Short-lived immunity after 17DD Yellow Fever single dose indicates that booster...

Campi-Azevedo, Ana Carolina; Reis, Laise Rodrigues; Peruhype-Magalh?es, Venessa; Reis, Jordana Grazziela Coelho dos; Antonelli, Lis Ribeiro

Funda??o de Amparo ? Pesquisa do Estado de Minas Gerais (FAPEMIG), BioManguinhos/FIOCRUZ, PROEP/IRR/FIOCRUZ, Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico-CNPq; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Oswaldo Cruz. Instituto Ren? Rachou. Belo Horizonte, MG, Brasil.; Funda??o Osw...

Date: 2019   |   Origin: Oasisbr

Multi-parameter approach to evaluate the timing of memory status after 17DD-YF ...

Costa-Pereira, Christiane; Campi-Azevedo, Ana Carolina; Coelho-dos-Reis, Jordana Grazziela; Peruhype-Magalh?es, Vanessa; Ara?jo, M?rcio Sobreira Silva

Programa Nacional de Imuniza??es (PNI), Secretaria de Vigil?ncia em Sa?de (SVS), PDTIS, CNPq (472782/2009-6 and 475076/2013-3), CAPES, FAPEMIG and PROEP/CPqRR/FIOCRUZ for financial support. ACCA and JGCdR received financial support from CNPq MCTI/CNPq/2014.; Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte, MG, Brazil.; Funda??o Oswaldo Cruz. Centro de Pesquisas Ren? Rachou. Belo Horizonte...

Date: 2018   |   Origin: Oasisbr

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