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Empowering portuguese-speaking women inTropical Health sciences:the journey of ...

Maurício, Isabel L.; Domingos, Ana; Arez, Ana Paula; Conceição, Cláudia; Couto, Isabel; Oliveira Martins, Maria do Rosário; Campino, Lenea

Female participation in science, including biomedical sciences, has increased, but still presents various challenges. The MulhereSTrop network was launched in 2015 to support women scientists in African Portuguese speaking countries (PALOP) inTropical Health.The network has offered workshops on scientific writing and has encouraged scientific article submission, with awards for the best. Through the website, th...


1,2,4-Trioxolane and 1,2,4,5-Tetraoxane endoperoxides against old-world Leishma...

Mendes, Andreia; Armada, Ana; Cabral, Lília; Amado, Patrícia; Campino, Lenea; Cristiano, Maria de Lurdes; Cortes, Sofia

Leishmaniasis remains one of the ten Neglected Tropical Diseases with significant morbidity and mortality in humans. Current treatment of visceral leishmaniasis is difficult due to a lack of effective, non-toxic, and non-extensive medications. This study aimed to evaluate the selectivity of 12 synthetic endoperoxides (1,2,4-trioxolanes; 1,2,4,5-tetraoxanes) and uncover their biochemical effects on <i>Leishmania...


Giardia duodenalis infection in dogs from the metropolitan area of Lisbon, Port...

Pereira, André; Teixeira, Joana; Sousa, Sofia; Parreira, Ricardo; Campino, Lenea; Meireles, José; Maia, Carla

Giardia duodenalis is a cosmopolitan enteric protozoan that affects a wide range of vertebrates, including humans and dogs. Genetic characterisation reveals eight different assemblages, with A and B having been found mainly in humans and several other animals, and thus considered potentially zoonotic, while C and D are adapted to infect dogs. This study aimed to determine the prevalence of G. duodenalis, their ...


Improved phylogeny of brown algae Cystoseira (Fucales) from the Atlantic-Medite...

Bruno De Sousa, Carolina; Cox, Cymon; Brito, Luís; Pavão, Maria Madalena; Pereira, Hugo; Ferreira, Ana; Ginja, Catarina; Campino, Lenea

Cystoseira is a common brown algal genus widely distributed throughout the Atlantic and Mediterranean regions whose taxonomical assignment of specimens is often hampered by intra- and interspecific morphological variability. In this study, three mitochondrial regions, namely cytochrome oxidase subunit 1 (COI), 23S rDNA (23S), and 23S-tRNAVal intergenic spacer (mt-spacer) were used to analyse the phylogenetic re...


Report of in vitro antileishmanial properties of Iberian macroalgae

Bruno De Sousa, Carolina; Lago, Joao Henrique G.; Macridachis, Jorge; Oliveira, Marta; Fonseca Brito, Luis; Vizetto-Duarte, Catarina; Florindo, Claudia

Here is reported the anti Leishmania infantum activity of 48 hexane, CH2Cl2 and MeOH extracts from 16 macroalgae collected on the Iberian Coast. Seven hexane and CH2Cl2 Cystoseira baccata, Cystoseira barbata, Cystoseira tamariscifolia, Cystoseira usneoides, Dictyota spiralis and Plocamium cartilagineum extracts were active towards promastigotes (IC50 29.8-101.8 mu g/mL) inducing strong morphological alterations...


Synopsys of the 3rd National Congress of Tropical Medicine and 1st Lusophone Co...

Lobo, Maria Luísa; Santos Costa, Sofia; Pinto Junior, Vitor Laerte; Salgueiro, Patrícia; Tavanez, João Paulo; Campino, Lenea

Currently, Tropical Medicine emerged as both an important medical specialty and scientific discipline assuming a preponderant global dimension. Until a few years ago, several tropical pathologies, which were exclusively associated with tropical regions, have been gradually expanding to other geographic areas previously considered free of these infections. Vectorborne diseases are included among this group of in...


Leishmaniasis in Portugal in the beginning of the XXI century

Maia, Carla; Campino, Lenea

Leishmaniasis caused by Leishmania infantum is a parasitic zoonosis in which the dog is the main host and reservoir. The parasites are transmitted to vertebrate hosts by phlebotomine sand flies being Phlebotomus perniciosus and P. ariasi the proven vector species in Portugal. Furthermore, the artificial transmission trough syringes and needles shared by drug addicts was proven in the eighties. Between the years...



DOENÇAS DA POBREZA, NEGLIGENCIADAS E EMERGENTES

Parreira, Ricardo; Campino, Lenea

The term neglected and poverty-related diseases, despite not being clearly defined, is usually regarded as synonym of a group of illnesses that primarily occur in developing count ries, where they severely impact the morbidity and mortality of the populat ions they afflict . Notwithstanding the absence, for some of them, of adequate prophylact ic as well as therapeut ic intervent ions, their persistence is very...



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