Funding Information: This work was supported by grants from the University of California Irvine Malaria Initiative (A17-0209) and from the Open Philanthropy Project (A22-2768-001).. Publisher Copyright: © The Author(s) 2025.; Context: This study was conducted to contribute to the design of a field trial of a novel genetic strategy aimed at the elimination of malaria. The strategy involves the introduction, esta...
Funding Information: Funding: This work was supported by Open Philanthropy Project, A20-3521 and A22-2768 and University of California Irvine Malaria Initiative, A17-0209. We thank National Malaria Control Program personnel from S\u00E3o Tom\u00E9 and Pr\u00EDncipe, and the Ministry of Health in S\u00E3o Tom\u00E9 and Pr\u00EDncipe who facilitated field collections in S\u00E3o Tom\u00E9. We thank Yoosook Lee fo...
Funding Information: We thank the National Malaria Control Program personnel from the Union of the Comoros for facilitating field collections in the islands. We thank the team of the Medical Entomology Unit of the Institut Pasteur de Madagascar for collecting and processing specimens from Madagascar. Funding Information: This work was supported by grants from the UC Irvine Malaria Initiative Program (A17- 0209)...
Funding Information: This work was supported by grants from the UC Irvine Malaria Initiative Program and Open Philanthropy. Funding Information: We thank National Malaria Control Program personnel from São Tomé and Príncipe and, the Ministry of Health in São Tomé and Príncipe who facilitated our field collections in São Tomé. Publisher Copyright: Copyright © 2022 Ditter, Campos, Pinto, Cornel, Rompão and Lanzar...
Funding Information: This work was supported by grants from the UC Irvine Malaria Initiative Program, Open Philanthropy and NIH R56 grant (R56AI130277). We thank the National Malaria Control Program personnel from São Tomé and Príncipe and, Ministry of Health in São Tomé and Príncipe who facilitated our field collections in São Tomé. We thank the Centre International de Recherches Médicales de Franceville (Fran...
We report the first complete mitogenome (Mt) sequence of Anopheles coustani, an understudied malaria vector in Africa. The sequence was extracted from one individual mosquito from São Tomé island. The length of the A. coustani Mt genome was 15,408 bp with 79.3% AT content. Phylogenetic analysis revealed that A. coustani is most closely related to A. sinensis (93.5% of identity); and 90.1% identical to A. gambia...
The increasing population of Aedes aegypti mosquitoes on Madeira Island (Portugal) resulted in the first autochthonous dengue outbreak, which occurred in October 2012. Our study establishes the first genetic evaluation based on the mitochondrial DNA (mtDNA) genes [cytochrome oxidase subunit I (COI) and NADH dehydrogenase subunit 4 (ND4)] and knockdown resistance ( kdr ) mutations exploring the colonisation hist...
Population genetic studies of insect vectors can generate knowledge to improve epidemiological studies focused on the decrease of pathogen transmission. In this study, we used nine SNPs across the Aedes aegypti genome to characterize seasonal population variations of this important dengue vector. Mosquito samples were obtained by ovitraps placed over Botucatu SP from 2005 to 2010. Our data show that, regardless...