38 documents found, page 1 of 4
Arquivos definitivos e minimização de dados: uma experiência no Arquivo Municip...
Campos, António; Patrício, SandraO Regulamento Geral de Proteção de Dados (RGPD), em vigor no espaço europeu desde 2018, tem como objetivo a proteção dos titulares dos dados no que respeita ao tratamento e utilização dos seus dados. Foi transposto para o regime jurídico português através da Lei n.º 58/2019 de 8 de agosto, e não derroga o Decreto-Lei n.º 16/93 de 23 de janeiro, alterado pela Lei n.º 16/2016 de 22 de agosto. Os dados pessoais de...
Pseudophakic macular edema: Review and new insights on treatment and prophylaxis
Campos, António; Mota, Carolina; Cruz, Henrique; Sousa, João PauloPseudophakic cystoid macular edema (PCME) is a common complication of cataract surgery that may rarely result in vision loss. In most cases PCME resolves spontaneously, which makes it challenging to establish the efficacy of therapeutic and prophylactic interventions. Although no consensus exists regarding management or prevention, most surgeons advocate prophylaxis primarily for high-risk eyes. Nevertheless, t...
Arquivo da Web local no Município de Sines: lições aprendidas e desafios futuros
Patrício, Sandra; Campos, António; Mestre, HélderAs coleções de periódicos do Arquivo Municipal de Sines; documentação nado-digitais; a imprensa e a comunidade digital; formas de preservação e colaboração com o Arquivo.pt.
Preserving visual acuity: a compelling 12-year case study of controlling neovas...
Tomás, Rita O.; Campos, António; Oliveira, Nuno; Soares, Pedro; Sousa, João P.Introduction: In neovascular age-related macular degeneration (nAMD) trials, anti-VEGF injection frequency decreases after the first year, while outcomes remain primarily related to the number of injections. To the best of our knowledge, there are no reports of maintaining the best corrected visual acuity (BCVA) for more than 7 years in extension studies. Objective To report a 12-year follow-up of a real-world ...
Improving cork polymer composites for the automotive industry
Campos, António; Martins, Carla I.; Batista, Álvaro[Excerpt] The pressure imposed by legislations and treaties to adopt more sustainable and eco-friendly alternative materials is rising. Therefore, the use of cork-polymer composites (CPC) in the automotive industry could bridge the difficulties they have complying with the environmental laws and the need of giving a second life to the cork industrial wastes. From the cork processing, residues are generated, als...
Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosome...
Jia, Lei-Jie; Rafiq, Muhammad; Radosa, Lukáš; Hortschansky, Peter; Cunha, Cristina; Cseresnyés, Zoltán; Krüger, Thomas; Schmidt, FranziskaThe decision whether endosomes enter the degradative or recycling pathway in mammalian cells is of fundamental importance for pathogen killing, and its malfunctioning has pathological consequences. We discovered that human p11 is a critical factor for this decision. The HscA protein present on the conidial surface of the human-pathogenic fungus Aspergillus fumigatus anchors p11 on conidia-containing phagosomes ...
Genetic determinants of fungi-induced ROS production are associated with the ri...
Matzaraki, Vasiliki; Beno, Alexandra; Jaeger, Martin; Gresnigt, Mark S.; Keur, Nick; Boahen, Collins; Cunha, Cristina; Gonçalves, Samuel M.; Leite, LuisReactive oxygen species (ROS) are an essential component of the host defense against fungal infections. However, little is known about how common genetic variation affects ROS-mediated antifungal host defense. In the present study, we investigated the genetic factors that regulate ROS production capacity in response to the two human fungal pathogens: Candida albicans and Aspergillus fumigatus. We investigated f...
MAVS expression in alveolar macrophages is essential for host resistance agains...
Wang, Xi; Cunha, Cristina; Grau, Madeleine S.; Robertson, Shelly J.; Lacerda, João; Campos, António; Lagrou, Katrien; Maertens, Johan; Best, Sonja M.Our recent data demonstrate a critical role of the RIG-I-like receptor family in regulating antifungal immunity against Aspergillus fumigatus in a murine model. However, the importance of this pathway in humans and the cell types that use this innate immune receptor family to detect A. fumigatus remain unresolved. In this study, using patients who underwent hematopoietic stem cell transplantation, we demonstrat...
Entrevista com Professor Sohan Singh Hayreh
Campos, António; Hayreh, Sohan SignhÉ uma honra e um enorme privilégio poder apresentar o Professor Sohan Singh Hayreh, muito justamente considerado “Uma lenda viva da Oftalmologia”. Como ficará patente para quem ler a entrevista, trata-se de alguém que desenvolveu intensa atividade médica e cirúrgica e ergueu várias vezes do zero verdadeiros laboratórios de investigação clínica. A sua atividade foi desenvolvida em três continentes, mercê de uma...
Glossário DIZERES - Recolha, documentação e preservação do vocabulário usado pe...
Campos, António; Encarnação, Carlos; Vilhena, Diogo; Chinita, Gonçalo; Mestre, Hélder; Gonçalves, Maria Filomena; Patrício, Sandra; Costa, SofiaO "Glossário DIZERES - Recolha, documentação e preservação do vocabulário usado pelas comunidades de Sines" reúne e ilustra uma parte do léxico e das expressões tradicionais daquela localidade.; Programa EDP Tradições