25 documents found, page 1 of 3
Identification of linezolid-resistant Enterococcus spp. in calves: findings fro...
Ribeiro, Alícia; Teixeira, Maria J.; Pinho, Luís; Campos, Carla; Novais, Carla; Peixe, Luísa; Brito, Nuno V.; Quinteira, Sandra; Miranda, CarlaBackground: Antimicrobial resistance (AMR) is a global health threat requiring a One Health approach, as antibiotic-resistant bacteria can spread between animals and humans. Enterococcus spp., particularly E. faecium (Efm) and E. faecalis (Efs), are key AMR indicators due to their role as gut commensals and their potential as reservoirs of resistance genes. They are also opportunistic pathogens that can cause s...
Diagnostic pitfalls in Staphylococcus spp. surveillance: lessons from a multina...
Pinheiro, Bárbara; Gomes-Sampaio, Luís M.; Pacheco, Patrícia; Campos, Carla; Braz, Maria Pranto; Coelho, Cristina; Miranda, Carla; Quinteira, SandraBackground: Staphylococcus aureus is a leading cause of severe and hard-to-treat human infections, particularly when resistant to cefoxitin due to the presence of the mecA gene [1]. However, diagnostic challenges arise from the misidentification of S. aureus and related species when relying on classical identification methods (mannitol fermentation; coagulase production), as well as from the detection of strain...
A cyclam salt as an antifungal agent: Interference with Candida spp. and Crypto...
Cerqueira, Fátima; Medeiros, Rui; Lopes, Inês; Campos, Carla; Ferraz, Maria Pia; Silva, Fernando; Alves, Luís G.; Pinto, EugéniaThe importance of fungal infections, particularly those caused by yeasts, is increasing among the medical community. Candida albicans and Cryptococcus neoformans are amongst the high-priority fungal species identified by the World Health Organization (WHO) and are considered in the critical group, while Candida krusei is included in the medium-priority group. The cyclam salt H4[H2(4-CF3PhCH2)2Cyclam]Cl4 proved ...
Mapping of key bacterial species for Postmorteminterval calculation
Ferreira, Ana Cláudia; Barbosa, Daniel J.; Campos, Carla; Oliveira, Ricardo Jorge Dinis; Freitas, Ana R.Estimation of the PostmortemInterval (PMI), the time elapsed since death, is one of the most challenging issues in forensic sciences. Most studies focus on extensive bacterial sequencing, but culture-based experiments for higher taxonomic resolution remain scarce. We aimed to analyze total bacterial counts and map Enterococcus faecalis, Staphylococcus aureusand Escherichia coliin different organs and timepoints...
Dairy cattle and the iconic autochthonous cattle in northern Portugal are reser...
Quinteira, Sandra; Dantas, Rui; Pinho, Luís; Campos, Carla; Freitas, Ana R.; Brito, Nuno V.; Miranda, Carla; Campos, CarlaAnimals destined for human consumption play a key role in potentially transmitting bacteria carrying antibiotic resistance genes. However, there is limited knowledge about the carriage of antibiotic-resistant bacteria in native breeds. We aimed to characterize the phenotypic profiles and antibiotic resistance genes in Escherichia coli isolated from bovines, including three native Portuguese bovine breeds. Forty...
Colistin-resistant Escherichia coli in calves and adult cattle from Portuguese ...
Ribeiro, Madalena F.; Pinho, Luís; V. Brito, Nuno; Campos, Carla; Freitas, Ana R.; Quinteira, Sandra; Miranda, CarlaBackground: Antimicrobial resistance poses a pressing and significant challenge, driven by the intricate interplay among animals, humans, and the environment [1]. Escherichia coli, a commensal within animal and human gut microbiota, stands as one of the most ubiquitous bacteria. With a multitude of resistance genes, many E. coli strains exhibit a multidrug-resistant phenotype, diminishing the effectiveness...
Mapping of key bacterial species for postmortem interval calculation
Cláudia-Ferreira, Ana; Barbosa, Daniel J.; Campos, Carla; Dinis-Oliveira, Ricardo Jorge; Freitas, Ana R.Background: Estimation of the Postmortem Interval (PMI), the time elapsed since death, is one of the most challenging issues in forensic sciences [1]. Most studies focus on extensive bacterial sequencing, but culture-based experiments for higher taxonomic resolution remain scarce [2]. Objective: We aimed to analyze total bacterial counts and map Enterococcus faecalis, Staphylococcus aureusand Escherichia coli i...
Antimicrobial activity of dimeric flavonoids
Lopes, Inês; Campos, Carla; Medeiros, Rui; Cerqueira, FátimaDistributed throughout the environment are various microorganisms such as bacteria, fungi, parasites, and viruses. Although many are part of the human microbiome, many are pathogenic and cause infections ranging from mild to severe. In recent years, the identification of multidrug-resistant microorganisms has become a serious public health problem. The resulting infections call into question the therapeutic cap...
Potential pathogenic and opportunistic oral bacteria in early life: the role of...
Fernandes, Mariana; Azevedo, Maria João; Campos, Carla; Ferreira, Ana Filipa; Azevedo, Álvaro; Falcão-Pires, Inês; Zaura, Egija; Ramalho, CarlaIn early life, maternal factors are of the utmost relevance for oral microbiome acquisition and maturation. Therefore, our study explored the impact of maternal factors, such as saliva and breastmilk colonization, cardiovascular risk factors (CRF), type of delivery, oral health, and caregiving habits on the prevalence of potential pathogenic and opportunistic oral bacteria in early life. A total of 26 healthy m...
Unveiling the relevance of the oral cavity as a staphylococcus aureus colonizat...
Campos, Joana; Faria Pires, Mariana; Sousa, Marta; Campos, Carla; Fernandes Ferreira Alves da Costa, Carolina; Sampaio-Maia, BeneditaStaphylococcus aureus is both a human commensal and a pathogen, that causes serious nosocomial and community-acquired infections. Despite nostrils being considered its preferred host habitat, the oral cavity has been demonstrated to be an ideal starting point for auto-infection and transmission. The antibiotic resistance assessment of S. aureus is a priority and is often reported in clinical settings. This stud...