2 documents found, page 1 of 1
Essential and non-essential elements, and volatile organic compounds for the di...
C.Gonçalves, Ana; Campos, Gonçalo; Pinto, Edgar; Oliveira, Ana Sofia; Almeida, Agostinho; Guedes de Pinho, Paula; Alves, Gilberto; R. Silva, LuísThe mineral contents and volatile profiles of 23 sweet cherry cultivars were determined. A total of 27 minerals were determined by ICP-MS and flame atomic absorption spectrometry, including 12 essential and 15 non- essential elements. K was the most abundant in all cultivars, while Tl was the one found in the smallest amounts. A total of 66 volatiles were identified using SPME/GC–MS, including 16 aldehydes, 23 ...
Synthesis, in vitro evaluation and QSAR modelling of potential antitumoral 3,4-...
Matias, Mariana; Campos, Gonçalo; Santos, Adriana O.; Falcão, Amílcar; Silvestre, Samuel; Alves, GilbertoA series of 3,4-dihydropyrimidin-2-(1H)-thiones (1–22) was synthesized through the Biginelli reaction in order to find novel anticancer drug candidates based on the structure of monastrol. The antiproliferative activity of the compounds was screened in several cell lines and the chlorinated compounds expressed considerable cytotoxicity in hepatic and/or colon and MCF-7 breast cancer cell lines. Within these, co...