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Potential Pathogenic and Opportunistic Oral Bacteria in Early Life: The Role of...

Fernandes, M; Azevedo, MJ; Campos, C; Ferreira, AF; Azevedo, A; Falcão-Pires, I; Zaura, E; Ramalho, C; Campos, J; Sampaio-Maia, B

In early life, maternal factors are of the utmost relevance for oral microbiome acquisition and maturation. Therefore, our study explored the impact of maternal factors, such as saliva and breastmilk colonization, cardiovascular risk factors (CRF), type of delivery, oral health, and caregiving habits on the prevalence of potential pathogenic and opportunistic oral bacteria in early life. A total of 26 healthy m...


From farm to fork: colistin voluntary withdrawal in Portuguese farms reflected ...

Ribeiro, S; Mourão, J; Novais, Â; Campos, J; Peixe, L.; Antunes, Patrícia


Dental pulp stem cells and Bonelike® for bone regeneration in ovine model

Campos, J; Sousa, A; Caseiro, A; Pedrosa, S; Pinto, P; Branquinho, M; Amorim, I; Santos, J; Pereira, T; Mendonça, C; Afonso, A; Atayde, L; Maurício, A

Development of synthetic bone substitutes has arisen as a major research interest in the need to find an alternative to autologous bone grafts. Using an ovine model, the present pre-clinical study presents a synthetic bone graft (Bonelike®) in combination with a cellular system as an alternative for the regeneration of non-critical defects. The association of biomaterials and cell-based therapies is a promising...


Non-typhoidal Salmonella in the Pig Production Chain: A Comprehensive Analysis ...

Campos, J; Mourão, J.; Peixe, L.; Antunes, Patrícia

<jats:p>Salmonellosis remains one of the most frequent foodborne zoonosis, constituting a worldwide major public health concern. The most frequent sources of human infections are food products of animal origin, being pork meat one of the most relevant. Currently, particular pig food production well-adapted and persistent Salmonella enterica serotypes (e.g., Salmonella Typhimurium, Salmonella 1,4,[5],12:i:-, Sal...


Linseed essential oil - Source of Lipids as Active Ingredients for Pharmaceutic...

Campos, J; Severino, P; Ferreira, C; Zielinska, A; Santini, A; Souto, S; Souto, EB

Linseed - also known as flaxseed -, is known for its beneficial effects on animal health attributed to its composition, comprising omega-6 (linoleic) and omega-3 (α-linolenic) fatty acids, various dietary fibers and lignans, which have health benefits in reducing the risk of cancer and cardiovascular diseases, lowering the levels of LDL-cholesterol and relaxing the smooth muscle cells in arteries increasing the...


mcr-1 in Carbapenemase-Producing Klebsiella pneumoniae in Hospitalized Patients...

Mendes, AC; Novais, A; Campos, J; Rodrigues, C; Santos, C; Antunes, Patrícia; Ramos, H; Peixe, L.

We describe a hospital-based outbreak caused by multidrug-resistant, Klebsiella pneumoniae carbapenemase 3-producing, mcr-1-positive K. pneumoniae sequence type 45 in Portugal. mcr-1 was located in an IncX4 plasmid. Our data highlight the urgent need for systematic surveillance of mcr-1 to support adequate therapeutic choices in the nosocomial setting.


Water supply and feed as sources of antimicrobial-resistant Enterococcus spp. i...

Novais, Carla; Campos, J; Freitas, AR; Barros, M; Silveira, E; Coque, TM; Antunes, Patrícia; Luisa Peixe

The role of European fish farms in the spread of antimicrobial-resistance in the environment and food chain, as well as possible sources of their contamination by clinically relevant antimicrobial-resistance bacteria is scarcely known. This study aimed to assess the contribution of Portuguese rural trout farms on dispersion of Enterococcus with antimicrobial-resistance and putative virulence genes in the enviro...


Inflow water is a major source of trout farming contamination with Salmonella a...

Antunes, Patrícia; Campos, J; Mourão, J.; Pereira, J; Novais, C.; Peixe, L.

The impact of European aquaculture, namely trout farms, in the spread of antibiotic resistance and/or zoonotic pathogens has been scarcely addressed. Moreover, aquaculture contamination sources and bacterial dissemination routes have been barely explored. In this study, we assessed the contribution of Portuguese land-based intensive rainbow trout farms and retailed market trout to the spread of Salmonella and b...


Imported poultry meat as a source of extended-spectrum cephalosporin-resistant ...

Campos, J; Mourao, J; Silveira, L; Saraiva, M; Correia, CB; Macas, AP; Luisa Peixe; Antunes, Patrícia

Extended-spectrum cephalosporin (ESC)-resistant Salmonella have been described at a low level in the EU, nevertheless the increasing importation of poultry meat could be an important source of epidemic strains carrying ESC resistance genes. This study evaluated ESC resistance and its genetic platform among Salmonella isolates from poultry meat products imported into Portugal as well as clonal relatedness of the...


Salmonellosis: the role of poultry meat

Antunes, Patrícia; Mourão, Joana; Campos, J; Peixe, Luísa

Salmonellosis remains one of the most frequent food-borne zoonoses, constituting a worldwide major public health concern. Currently, at a global level, the main sources of infection for humans include meat products, including the consumption of contaminated poultry meat, in spite of the success of Salmonella control measures implemented in food-animal production of industrialized countries. In recent years, a s...


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