24 documents found, page 1 of 3
C-Ring Oxidized Estrone Acetate Derivatives: Assessment of Antiproliferative Ac...
Canário, Catarina; Matias, Mariana; Brito, Vanessa; Pires, Patrícia; Santos, Adriana O.; Falcão, Amílcar; Silvestre, Samuel; Alves, GilbertoC-Ring oxidized estrone acetate derivatives as antiproliferative agents were prepared and tested against five cancer cell lines by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Flow cytometry assays to evaluate cell viability and modifications in cell cycle phases and molecular docking research against estrogen receptor α, steroid sulfatase, and 17β-hydroxysteroid dehydrogenase type 1 ...
Delivering Group Lifestyle Triple P through digital practice: A case study with...
Canário, Catarina; Abreu-Lima, Isabel; Silva-Martins, Marco; Campos, Joana; Rodrigues, Catarina Enes; Tavares, Mónica; Mansilha, Helena; Torres, SandraThe purpose of the current study was to explore the delivery of the Group Lifestyle Triple P (GLTP) parent group programme through digital practice. Eight mothers of obese children aged 6–11 were recruited from a university hospital. Using a mixed-methods approach, the study sought to characterise the perceived changes throughout the intervention and explore the outcome measures on children’s BMI z-score, weigh...
New Estrone Oxime Derivatives: Synthesis, Cytotoxic Evaluation and Docking Studies
Canário, Catarina; Matias, Mariana; Brito, Vanessa; Santos, Adriana O.; Falcão, Amílcar; Silvestre, Samuel; Alves, GilbertoThe interest in the introduction of the oxime group in molecules aiming to improve their biological effects is increasing. This work aimed to develop new steroidal oximes of the estrane series with potential antitumor interest. For this, several oximes were synthesized by reaction of hydroxylamine with the 17-ketone of estrone derivatives. Then, their cytotoxicity was evaluated in six cell lines. An estrogenici...
Adaptation and validation of a measure of students’ adaptive and maladaptive wa...
Gonçalves, Teresa; Lemos, Marina S.; Canário, CatarinaLittle research has, to date, explored students’ coping in the academic domain. Yet, children and adolescents frequently refer daily academic difficulties as a common source of stress. The ways children respond to academic demands have the potential to make a difference in their learning and achievement. Therefore, the availability of a measure of academic coping is of critical importance to expand educational ...
Couples' psychological adjustment to twin parenthood: mode of conception (spont...
Tendais, Iva Alexandra Barbosa; Figueiredo, Bárbara; Canário, Catarina; Kenny, David A.Aim: To examine whether mode of conception and gender are associated with parents’ psychological adjustment across the transition to twin parenthood. Background: There is limited knowledge on the psychological adjustment of couples to twin parenthood during pregnancy and early postpartum, especially for fathers. The available research suggests that first-time mothers of twins conceived by assisted reproduction ...
Questionário de Estilos Educativos Parentais revisto (QEEP-r) : estudo psicomét...
Cruz, Orlanda; Canário, Catarina; Ducharne, Maria BarbosaResumo: Este artigo apresenta o Questionário de Estilos Educativos Parentais revisto (QEEP-r), que oferece uma medida da perceção dos adolescentes quanto aos estilos educativos parentais (tal como a sua primeira versão, o QEEP), mas distinguindo o alvo da avaliação em pai e mãe e focando a dimensão da promoção da autonomia. São estudadas as propriedades psicométricas e avaliada a invariância da escala quanto ao...
Couples’ relationship affects mothers’ and fathers’ anxiety and depression traj...
Figueiredo, Bárbara; Canário, Catarina; Tendais, Iva Alexandra Barbosa; Pinto, Tiago Miguel; Kenny, David A.; Field, TiffanyBackground: The association between the couple relationship and the mothers’ and fathers’ psychological adjustment to the transition to parenthood has been examined in the literature. However, the direction of effects between these variables has not been extensively explored. This study aimed to assess the direction of effects between mothers’ and fathers’ positive and negative interactions and anxiety and depr...
Parenting Behavior Questionnaire revised (QEEP-r): Psychometric study and measu...
Cruz, Orlanda; Canário, Catarina; Barbosa-Ducharne, MariaThe current study presents the Parenting Behavior Questionnaire revised (QEEP-r), which offers a measure of adolescents’ perceptions of father and mother’s parenting behaviors (as its first version QEEP), however distinguishing the target of the assessment between father and mother and focusing the dimension autonomy support. Psychometric properties of the measure are addressed as well as measurement invariance...
Anxiety and depressive symptoms in women and men from early pregnancy to 30 mon...
Canário, Catarina; Figueiredo, BárbaraAims: The aims of this study were to analyse the changes in anxiety and depression symptoms from early pregnancy to 30 months postpartum according to gender and parity. Method: 129 couples (N = 258) recruited from an obstetrics unit completed self-report measures of anxiety and depression at each pregnancy trimester, childbirth, 3 and 30 months postpartum. Using multilevel modelling, piecewise dyadic growth cur...
Benzodiazepinas e o acompanhamento psicológico dos utentes de um centro de saúd...
Regalado, Joana; Rocha, José Carlos; Duarte, Ivone; Canário, Catarina; Sampaio, Inês; Marina, Sílvia; Ricou, MiguelO uso inadequado de benzodiazepinas é um problema de saúde pública bem conhecido e, por isso, é particularmente relevante a sua monitorização e a implementação de soluções adequadas. Pretendemos conhecer a realidade dos utentes de um Centro de Saúde na Cidade do Porto relativamente ao consumo de benzodiazepinas, bem como a sua relação com o acompanhamento psicológico passado, atual ou futuro por parte dos mesmo...