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Osteoporosis management during the COVID-19 pandemic - Position paper
Rodrigues, Ana M; Romeu, José Carlos; Canas da Silva, José; Tavares-Costa, José; Faustino, Augusto; Vaz, Carlos; Pereira da Silva, José Antóniover; COVID-19 pandemic significantly increased the already large number of victims of osteoporosis in Portugal. Osteoporosis outpatient clinics were either closed or had limited presential appointments. Many hospitals reduced orthopaedic services to make space for patients with COVID-19. In addition, the volunteer or forced sedentarism, as imposed by the pandemic, increased the risk of falls and fractures drast...
TRAF1/C5 but not PTPRC variants are potential predictors of rheumatoid arthriti...
Canhão, Helena; Maria Rodrigues, Ana; Santos, Maria José; Carmona-Fernandes, Diana; Bettencourt, Bruno F.; Cui, Jing; Rocha, Fabiana L.Background. The aim of our work was to replicate, in a Southern European population, the association reported in Northern populations between PTPRC locus and response to anti-tumor necrosis factor (anti-TNF) treatment in rheumatoid arthritis (RA). We also looked at associations between five RA risk alleles and treatment response. Methods. We evaluated associations between anti-TNF treatment responses assessed b...
Comparative effectiveness of tocilizumab and TNF inhibitors in rheumatoid arthr...
Romão, Vasco C.; Santos, Maria José; Polido-Pereira, Joaquim; Duarte, Cátia; Nero, Patrícia; Miguel, Cláudia; Costa, José António; Bernardes, MiguelObjectives. To compare the effectiveness of TNF inhibitors (TNFi) and tocilizumab in rheumatoid arthritis (RA) treatment, according to different response criteria. Methods. We included RA patients registered in the Rheumatic Diseases Portuguese Register treated with TNFi or tocilizumab for at least 6 months, between January 2008 and July 2013. We assessed remission/low disease activity (LDA) at 6 months accordi...