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Changes In HER2 And Hormonal Receptors Biomarkers After Neoadjuvant Chemotherap...

Ferreira Pinto, Paula; Peyroteo, Mariana; Castro, Luís; Canotilho, Rita; Correia, Ana Margarida; Baía, Catarina; Ribeiro, Cátia; Antunes, Pedro

 Introduction: Breast cancer biological subtype has an important impact in the definition of the treatment strategy and the prognosis. However, the influence of neoadjuvant chemotherapy in the immunohistochemistry profile of the tumor is not well clarified. This study aims to evaluate the incidence of immunohistochemistry profile changes after neoadjuvant chemotherapy and the impact of these changes in adj...

Date: 2024   |   Origin: Revista Portuguesa de Cirurgia

DEEP VENOUS THROMBOSIS AS THE FIRST MANIFESTATION OF HIBERNOMA - CLINICAL CASE

Mesquita, Ana; Vidoedo, José; Maia, Miguel; Canotilho, Rita; Afonso, Mariana

We present a 36 year-old female patient with a popliteo-femoral deep vein thrombosis whose further workup revealed a thigh tumor later diagnosed as hibernoma. Hibernoma is a very rare benign tumor stemming from vestigial remnants of fetal brown adipose cells, usually disclosed as a slow and painless growing, mass. It is impossible to distinguish it on clinical grounds from the more aggressive and ominous liposa...


THE IMPACT OF LIVER SURGERY AND MARGIN STATUS ON SURVIVAL ACCORDING TO KRAS MUT...

Peyroteo, Mariana; Canotilho, Rita; Sousa, Alexandre; Sousa, Fernanda; Fernandes, Manuel; Gonçalves, Belarmino; Videira, José Flávio; Fragoso, Maria

Introduction: The impact of kirsten rat sarcoma viral oncogene homolog (KRAS) mutational status on surgery planning for colorectal liver metastases (CRLM) remains unknown. The aim of the study was to evaluate the impact of type of liver surgery and margin status in recurrence free survival (RFS) of patients with CRLM, according to KRAS mutational status. Materials and methods: Retrospective review of all patien...

Date: 2020   |   Origin: Revista Portuguesa de Cirurgia

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