3 documents found, page 1 of 1
Evaluation of KIM-1 as an early biomarker of snakebite-induced AKI in mice
Dantas, Rodrigo Tavares; Sampaio, Tiago Lima; Lima, Dânya Bandeira; Menezes, Ramon Róseo Paula Pessoa Bezerra de; Canuto, Jader AlmeidaMade available in DSpace on 2018-12-11T17:21:02Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-09-01; Acute kidney injury (AKI) is one of the most important complications of bothropic poisoning and its early identification remains challenging. The nephrotoxicity of Bothrops insularis venom (BinsV) was previously described by our research group. In this study, we continued to evaluate the effect of BinsV...
Betulinic acid induces cell death by necrosis in Trypanosoma cruzi
Sousa, Paloma Leão; Souza, Racquel Oliveira da Silva; Tessarolo, Louise Donadello; Menezes, Ramon Róseo Paula Pessoa Bezerra de; Sampaio, Tiago LimaChagas ’ disease is a neglected disease caused by the protozoan parasite Trypanosoma cruzi and constitutes a serious health problem worldwide. The treatment is limited, with variable e ffi cacy of benznidazole and ni- furtimox. Betulinic Acid (BA), a triterpene, can be found in medicinal herbs and has a wide variety of biological and pharmacological activities. The objective was to evaluate betulinic acid e ff ...
Antimicrobial effect of Dinoponera quadriceps (Hymenoptera: Formicidae) venom a...
Lima, Danya Bandeira; Torres, Alba Fabíola Costa; Mello, Clarissa Perdigão; Menezes, Ramon Róseo Paula Pessoa Bezerra; Sampaio, Tiago LimaAims: Dinoponera quadriceps venom (DqV) was examined to evaluate the antibacterial activity and its bactericidal action mechanism against Staphylococcus aureus. Methods and Results: DqV was tested against a standard strain of methicillinsensitive Staphylococcus aureus (MSSA), Staph. aureus ATCC 6538P and two standard strains of methicillin-resistant Staphylococcus aureus (MRSA), Staph. aureus ATCC 33591 and Sta...