Introduction: Multiple sclerosis management has progressed significantly due to the development of novel treatments. Thus, assessing the patients’ treatment response is essential to optimize therapeutic decisions. This study aimed to establish a national consensus on the assessment and monitoring of the response to multiple sclerosis treatment with disease-modifying therapies. Methods: The Delphi methodology wa...
Material Extrusion (MEX) process is increasingly used to fabricate components for structural applications, driven by the availability of advanced materials and greater industrial adoption. In these contexts, understanding the mechanical performance of printed parts is crucial. However, conventional methods for assessing anisotropic elastic behavior often rely on expensive equipment and time-consuming procedures...
In this article, the in-plane dynamic elastic properties of an E-glass randomly oriented fiber-reinforced SR GreenPoxy 56 composite were obtained based on the procedure specified in the ASTM E1876-21 standard. The experimental frequencies and the ones predicted by the simulation of the experimental procedure using a finite element analysis developed in the Patran/Nastran 2021 package were used in an iterative a...
This study examines how digital technologies influence the competitiveness of manufacturing small- and medium-sized enterprises (SMEs), with a focus on labor productivity and export performance. Using a sample of 669 firms in the Portuguese ornamental stone sector, a framework was applied to evaluate five levels of digital maturity through a quantitative approach. This analysis covers five years after the inves...
Multiple sclerosis (MS) is a chronic autoimmune-mediated neurodegenerative disease characterized by inflammation, demyelination, and axonal/neuronal damage in the central nervous system. In Portugal, the prevalence of MS is approximately 64.4 per 100 000 individuals. It is typically diagnosed in young adults aged 30 to 40, with a higher incidence in women, although it can also affect children/adolescents and th...
The healthcare context is undergoing a significant transformation, facing a series of complex and unprecedented challenges. This transformation is triggered by accessibility constraints to healthcare services, increased expectations from patients and sing financial burdens. Rather than being seen as unsolvable obstacles, these challenges can be perceived as powerful stimuli, encouraging the search for innovativ...
.; .
Introduction: Multiple sclerosis is a disease with a heterogeneous evolution. The early identification of secondary progressive multiple sclerosis is a clinical challenge, which would benefit from the definition of biomarkers and diagnostic tools applicable in the transition phase from relapsing-remitting multiple sclerosis to secondary progressive multiple sclerosis. We aimed to reach a Portuguese national con...
Additive manufacturing is a key technology for the digital production of customized prostheses and orthoses. Considering that such assistive devices can be designed to meet specific biomechanical needs based on the actual contours of the patients’ limbs, the ability of those having physical disabilities being able to produce their custom prostheses and orthoses at home would be groundbreaking, by current standa...