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Effects of testosterone, 17beta-estradiol, and downstream estrogens on cytokine...

Janele, D; Lang, T; Capellino, S; Cutolo, M; Pereira da Silva, JA; Straub, RH

Estrogens at physiological concentrations are thought to play an immune-stimulating role, whereas androgens have an anti-inflammatory impact. However, their role on cytokine secretion in the presence or absence of cortisol has not been investigated. Furthermore, the role of hydroxylated estrogens downstream of 17beta-estradiol (E2) on secretion of tumor necrosis factor (TNF) is not known. In this study on perip...

Date: 2006   |   Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
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