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Maximal Oxygen Uptake and Ventilation Improvement Following Sacubitril-Valsarta...

Valentim Gonçalves, A; Pereira-da-Silva, T; Galrinho, A; Rio, P; Soares, RM; Feliciano, J; Ilhão Moreira, R; Silva, S; Alves, S; Capilé, E

Background: Sacubitril/valsartan had its prognosis benefit confirmed in the PARADIGM-HF trial. However, data on cardiopulmonary exercise testing (CPET) changes with sacubitril-valsartan therapy are scarce. Objective: This study aimed to compare CPET parameters before and after sacubitril-valsartan therapy. Methods: Prospective evaluation of chronic heart failure (HF) patients with left ventricular ejection frac...


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