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Wear of Titanium Implant Platforms with Different Abutment Connections and Abut...

Mendes, Teresa A.; Vilhena, Luis M.; Portugal, Jaime; Caramês, João; Ramalho, Amílcar L.; Lopes, Luis P.

The most commonly used material in dental implants and their abutments is titanium. Zirconia is a more aesthetic alternative to titanium abutments; however, it is much harder. There are concerns that zirconia could damage the surface of the implant over time, especially in less stable connections. The aim was to evaluate the wear of implants with different platforms connected to titanium and zirconia abutments....


Bio-piezoelectric ceramic composites for electroactive implants—biological perf...

Fernandes, Beatriz Ferreira; Silva, Neusa; Marques, Joana Faria; Da Cruz, Mariana Brito; Tiainen, Laura Katariina; Gasik, Michael

Barium titanate (BaTiO<sub>3</sub>) piezoelectric ceramic may be a potential alternative for promoting osseointegration due to its piezoelectric properties similar to bone electric potentials generated in loading function. In this sense, the aim of this in vitro study was to evaluate the cellular response of human osteoblasts and gingival fibroblasts as well as the impact on <i>S. oralis</i> when in contact wit...


Modification of Zirconia implant surfaces by Nd:YAG laser grooves: does it chan...

da Cruz, Mariana Brito; Marques, Joana Faria; Marques, Ana Filipa Silva; Madeira, Sara; Carvalho, Óscar; Silva, Filipe Samuel; Caramês, João

The aim of this study was to evaluate gingival fibroblasts and human osteoblasts’ response to textured Nd:YAG laser microgrooves, with different dimensions, on zirconia implant surfaces. A total of 60 zirconia disks (8 mm in diameter and 2 mm in thickness) were produced and divided between four study groups (N = 15): three laser-textured (widths between 125.07 ± 5.29 μm and 45.36 ± 2.37 μm and depth values from...


Human gingival fibroblast and osteoblast behavior on groove-milled zirconia imp...

Cruz, Mariana Brito da; Marques, Joana Faria; Silva, Neusa; Madeira, Sara Cristina Soares; Carvalho, Óscar Samuel Novais; Silva, Filipe Samuel

Two type of cells representing periodontal hard tissues (osteoblasts) and soft tissues (fibroblasts) were evaluated in response to microgroove-milled zirconia surfaces. A total of 90 zirconia discs were randomly assigned to four width-standardized milling microgroove-textured groups and a control group without grooves (UT). The sandblast and acid-etch protocol were applied to all samples. Both cell lines were c...


Porous zirconia blocks for bone repair: an integrative review on biological and...

Resende-Gonçalves, Cláudia Inês; Sampaio, Nuno; Moreira, Joaquim; Carvalho, Oscar; Caramês, João; Manzanares-Céspedes, Maria Cristina

The aim of this study was to conduct an integrative review of the biological and mechanical outcomes of porous zirconia structures for extensive bone repair. An electronic search was performed on the PubMed database using a combination of the following scientific terms: porous, scaffold, foam, zirconia, bone regeneration, bone repair, bone healing. Articles published in the English language up to December 2021 ...


Biomimetic implant surfaces and their role in biological integration—a concise ...

Cruz, Mariana Brito; Silva, Neusa; Marques, Joana Faria; Mata, António; Silva, Filipe Samuel; Caramês, João

Background: The increased use of dental implants in oral rehabilitation has been followed by the development of new biomaterials as well as improvements in the performance of biomaterials already in use. This triggers the need for appropriate analytical approaches to assess the biological and, ultimately, clinical benefits of these approaches. Aims: To address the role of physical, chemical, mechanical, and bio...


Tooth-derived matrix granules for enhanced bone healing: chemical composition, ...

Souza, Júlio C. M.; Escobar, Mario; Pimentel, Inês Sofia; Caramês, João; Teughels, Wim; Silva, Filipe; Henriques, Bruno

Bone grafting has increasingly been used in surgical procedures for enhanced bone augmentation. Tooth-derived graft material has received considerable attention due to its chemical composition and autogenous source that can improve bone tissue healing. The main aim of this study was to provide a short and comprehensive review on the chemical composition, morphological aspects, and clinical outcomes of bone graf...


Human gingival fibroblast and osteoblast behavior on groove-milled zirconia imp...

Brito da Cruz, Mariana; Marques, Joana; Silva, Neusa; Madeira, Sara; Carvalho, Óscar; Silva, Filipe Samuel; Caramês, João; Mata, António

Two type of cells representing periodontal hard tissues (osteoblasts) and soft tissues (fibroblasts) were evaluated in response to microgroove-milled zirconia surfaces. A total of 90 zirconia discs were randomly assigned to four width-standardized milling microgroove-textured groups and a control group without grooves (UT). The sandblast and acid-etch protocol were applied to all samples. Both cell lines were c...


Biomimetic implant surfaces and their role in biological integration: a concise...

Brito da Cruz, Mariana; Silva, Neusa; Marques, Joana; Mata, António; Silva, Felipe Samuel; Caramês, João

Background: The increased use of dental implants in oral rehabilitation has been followed by the development of new biomaterials as well as improvements in the performance of biomaterials already in use. This triggers the need for appropriate analytical approaches to assess the biological and, ultimately, clinical benefits of these approaches. Aims: To address the role of physical, chemical, mechanical, and bio...


The synergistic effect of platelet-rich fibrin (PRF) and bone substitutes

Noronha, Miguel; Hotza, Dachamir; Henriques, Bruno; Silva, Filipe; Caramês, João; C. M. Souza, Júlio

The purpose of this study was to perform a narrative review on the synergistic effect of the combination of PRF and bone grafts. The literatre data reports that the mixture of PRF to bone substitutes accelerates bone formation in small bone defects. There is no consensus in the literature regarding the effects on larger bone defects. The addition of PRF allows the use of a low amount of particulate grafts, thus...


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