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Severe and Malignant Hypertension Are Common in Primary Atypical Hemolytic Urem...

Cavero, T; Arjona, E; Soto, K; Caravaca-Fontán, F; Rabasco, C; Bravo, L, et al.

Malignant hypertension is listed among the causes of secondary thrombotic microangiopathy, but pathogenic mutations in complement genes have been reported in patients with hypertension-induced thrombotic microangiopathy. Here we investigated the frequency and severity of hypertension in 55 patients with primary atypical hemolytic uremic syndrome (aHUS). A genetic analysis was performed in all patients, and fund...


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