2 documents found, page 1 of 1
Management of ibrutinib treatment in patients with B-cell malignancies: clinica...
Carda, José Pedro; Santos, Lurdes; Mariz, José Mário; Monteiro, Pedro; Gonçalves, Humberto Miguel; Raposo, João; Silva, Maria Gomes daIbrutinib, a potent inhibitor of the Bruton tyrosine kinase, has revolutionized the treatment of many B-cell malignancies. Ibrutinib has an established favorable toxicity profile with up to 8 years of experience in clinical trials; however, despite ibrutinib's favorable toxicity profile, dose reductions and treatment discontinuations are becoming more evident in clinical practice, particularly in the setting of...
ERYTHEMA NODOSUM – A RARE MANIFESTATION OF NON- HODGKIN LYMPHOMA
Estêvão, Dália; Carda, José Pedro; Louro, Emília; Carvalho, Armando; Costa, José Manuel NascimentoErythema nodosum (EN) is a panniculitis that presents with painful erythematous nodular lesions, pre- ferentially located on the extensor surface of the legs. EN is generally self-limited and chronic or recurrent lesions are rare. Its most common causes are streptococcal pharyngitis, sarcoidosis, inflammatory bowel disease and tuberculosis. A 73-year-old woman presented with recurrent EN with a year of evolutio...