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Progesterone and brassinosteroids synergistically enhance progesterone removal ...

Pinto, A; da Silva, DC; Cardoso, A; Fernandes, F; Soares, C; Patricia Valentao; Fernanda Fidalgo; Jorge Teixeira

Progesterone (PROG) has been detected at various concentrations in the environment and has adverse effects on humans and wildlife. This work evaluated the impact of PROG in Solanum nigrum L. plants, its removal capacity, and how 2,4-epibrassinolide (24-EBL) affects this process. Three treatments were used: (1) control, (2) irrigation with 0.8 mu M PROG, and (3) treatment with 0.8 mu M PROG after a pre-treatment...


Plastic toy soldiers, a lost battle? – an analytical perspective

Pereira, A; Candeias, A; Cardoso, A; Mirão, J; Caldeira, A Teresa

The conservation and preservation of museum collections requires a detailed understanding of their constituent materials which are often natural, synthetic or semi-synthetic polymers. The use of a wide variety of instrumental techniques can give an extraordinary amount of quality information, by delivering complementary data regarding composition and structure. This study was triggered by the Oporto Military Mu...


Interleukin-10 induces interferon-γ-dependent emergency myelopoiesis

Cardoso, A; Martins, AC; Maceiras, AR; Liu, W; Castro, I; Castro, AG; Bandeira, A; Di Santo, JP; Cumano, A; Li, Y; Vieira, P; Saraiva, M

In emergency myelopoiesis (EM), expansion of the myeloid progenitor compartment and increased myeloid cell production are observed and often mediated by the pro-inflammatory cytokine interferon gamma (IFN-γ). Interleukin-10 (IL-10) inhibits IFN-γ secretion, but paradoxically, its therapeutic administration to humans causes hematologic changes similar to those observed in EM. In this work, we use different in vi...


Massive Osteolytic Lesion of the Femur after Total Knee Arthroplasty.

Cardoso, A; Amaro, P; Gamelas, P; Carvalho, E; Silva, R; Oliveira, MH; Jesus, M

Various failure mechanisms have been identified in total knee arthroplasty (TKA). We hereby present one case of failure, which stands out because of its rapid and destructive progression. We report the case of a 72-year-old Caucasian female patient who developed a large bone osteolytic lesion of the femur after TKA. The patient presented to our hospital 7 years after the initial surgery, complaining of persiste...


Dietary interventions in Fibromyalgia: a systematic review

Silva, AR; Bernardo, A; Costa, J; Cardoso, A; Santos, P; Mesquita, MFd; Vaz Patto, J; Moreira, Pedro; Silva, ML; Padrão, Patrícia


Analytical characterization of the palette and painting techniques of Jorge Afo...

Antunes, V; Candeias, A; Mirao, J; Carvalho, ML; Dias, CB; Manhita, A; Cardoso, A; Francisco, M; Lauw, A; Manso, M

In this work, a study on a set of paintings from the most significant altarpiece assigned to Master Jorge Afonso (c. 1470–1540) painting workshop is presented. This altarpiece is composed by fourteen paintings made to the church of Convento de Jesus, in Setúbal, Portugal, and was made circa 1517–19/1530, according to art-history. This set of paintings is compared to one of the other most important Portuguese al...


Micro-Raman spectroscopy and complementary techniques (hXRF, VP-SEM-EDS, μ-FTIR...

Coccato, A; Costa, Mafalda; Rousaki, A; Clist, B; Karklins, K; Bostoen, K; Manhita, A; Cardoso, A; Dias, CB; Candeias, A; Moens, L; Mirao, J

In the framework of the inter-disciplinary KongoKing project, a set of beads from archaeological excavations in the Democratic Republic of the Congo was analysed by means of a minimally invasive, multi-analytical approach based on micro-Raman spectroscopy. The full characterization of the materials, including glassy network, opacifiers and colorizers, was achieved thanks to the combination of data from handheld...


Quo Vadis?: descodificar para bem intervencionar. O Contributo do estudo técnci...

Veiga, R; Brito, A; Valadas, S; Cardoso, A; Candeias, A; Pereira, L

Neste artigo são apresentados os principais resultados da investigação científica da pintura relativamente ás técnicas e materiais do suporte lenhoso, preparação, desenho subjacente e camadas pictóricas; assim como as principais intervenções de que foi alvo ao longo do tempo e que tiveram um forte impacto na sua leitura


The Dynamics of Interleukin-10-afforded protection during dextran sulfate sodiu...

Cardoso, A; Castro, A; Martins, AC; Carriche, GM; Murigneux, V; Castro, I; Cumano, A; Vieira, P; Saraiva, M

Inflammatory bowel disease encompasses a group of chronic-inflammatory conditions of the colon and small intestine. These conditions are characterized by exacerbated inflammation of the organ that greatly affects the quality of life of patients. Molecular mechanisms counteracting this hyperinflammatory status of the gut offer strategies for therapeutic intervention. Among these regulatory molecules is the anti-...


Identification and removal of nonoriginal layers in the 16th century paintings ...

Gomes, S; Ferreira, C; Nascimento, G; Piorro, L; Cardoso, A; Candeias, A; Lorena, M

This article is an outcome of the study, deci-sions, and restoration work undertaken during the inte-grated conservation project of the 16th century paintingsof Funchal’s Cathedral main chapel’s altarpiece, inMadeira Island, Portugal. After diagnostic research hasallowed a complete understanding of the original mate-rial of the 12 Portuguese–Flemish paintings, it has beenrevealed the presence of other superimpo...


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