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Hypothermia Does Not Boost the Neuroprotection Promoted by Umbilical Cord Blood...

Serrenho, Inês; Cardoso, Carla M.; Grãos, Mário; Dinis, Alexandra; Manadas, Bruno; Baltazar, Graça

Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the leading causes of death and long-term disability in the perinatal period. Currently, therapeutic hypothermia is the standard of care for this condition with modest efficacy and strict enrollment criteria. Therapy with umbilical cord blood cells (UCBC) has come forward as a strong candidate for the treatment of neonatal HIE, but no preclinical studies ...


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