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Massive Blood Loss from Urethrorrhage in a 16-year-old boy: Case Report and Rev...

Ascensão, J; Sobral, MC; Lima, S; Vaz Silva, A; Pratas Vital, V; Cardoso, D; Alves, F; Alves, R

Urethral varices and hemangiomas are rare, underreported conditions that can be asymptomatic or present with intermittent urethrorrhage that can start or worsen with erection, sexual intercourse and ejaculation. Diagnosis can be made with urethroscopy and there are a wide variety of possible treatments that can suit both conditions. We present a case of a pediatric patient with severe blood loss from urethral v...


The role of outer membrane protein(S) harboring slh/oprb-domains in extracellul...

Cardoso, D; Lima, S; Matinha-Cardoso, J; Tamagnini, P; Oliveira, P

Cyanobacteria are a group of photosynthetic prokaryotes that contribute to primary production on a global scale. These microorganisms release vesicles to the extracellular environment, spherical nanosized structures, derived essentially from the outer membrane. Even though earlier works in model Gram-negative bacteria have hypothesized that outer membrane stability is crucial in vesicle formation, the mechanism...


Impact of Physical Activity and Exercise on Bone Health in Patients with Chroni...

Cardoso, D; Marques, E; Leal, D; Ferreira, A; Baker, L; Smith, A; Viana, J

Background: Chronic Kidney Disease (CKD) patients frequently develop life-impairing bone mineral disorders. Despite the reported impact of exercise on bone health, systematic reviews of the evidence are lacking. This review examines the association of both physical activity (PA) and the effects of different exercise interventions with bone outcomes in CKD. Methods: English-language publications in EBSCO, Web of...


Primary Hyperoxaluria type 1 – Two Case Reports

Ganhão, I; Borges, C; Amorim, M; Braga da Cruz, M; Nobre, S; Francisco, T; Cardoso, D; Abranches, M

Primary hyperoxaluria type 1 is a rare autosomal recessive inherited disease, caused by mutations in AGXT gene, with an estimated incidence of 1:100.000 live births per year in Europe. Over 50% present with end stage renal disease at diagnosis. Case reports: The first case is a 14‑year‑old boy, second child to consanguineous parents, with history of recurrent lithiasis and ureteral dilatation starting 5 years b...


Pieloplastia Laparoscópica em Idade Pediátrica

Morão, S; Pratas Vital, V; Vaz Silva, A; Cardoso, D; Alves, F; Catela Mota, F; Pascoal, J

Introdução: A obstrução da junção pielo-ureteral (OJPU) é a causa congénita mais comum de uropatia obstrutiva na criança. O objectivo deste trabalho é documentar a experiência desta Unidade de Urologia Pediátrica relativamente às primeiras 20 pieloplastias realizadas por via laparoscópica. Material e Métodos: Estudo retrospectivo em que foram incluídos vinte doentes com o diagnóstico de OJPU submetidas a pielop...


Dilatação Endoscópica de Balão para Tratamento de Megaureter Obstrutivo Primári...

Morão, S; Pratas Vital, V; Cardoso, D; Alves, F; Catela Mota, F; Pascoal, J

Introduction: Congenital obstructive megaureter may be treated with endoscopic balloon dilatation, particularly in children under one year of age. We report our experience over a six year period. Methods: All patients with diagnosis of primary obstructive megaureter treated with endoscopic balloon dilatation from 2009 to 2014 (6 years) were included. The diagnosis of primary obstructive megaureter was based on ...


Impact of splenic artery ligation after major hepatectomy on liver function, re...

Carrapita, J; Abrantes, AM; Campelos, S; Gonçalves, AC; Cardoso, D; Sarmento-Ribeiro, AB; Rocha, C; Santos, JN; Botelho, MF; Tralhão, JG; Farges, O

It was reported that prevention of acute portal overpressure in small-for-size livers by inflow modulation results in a better postoperative outcome. The aim is to investigate the impact of portal blood flow reduction by splenic artery ligation after major hepatectomy in a murine model. Forty-eight rats were subjected to an 85% hepatectomy or 85% hepatectomy and splenic artery ligation. Both groups were evaluat...


Obstrução da Junção Pieloureteral por Pólipos Fibroepiteliais em Idade Pediátrica

Knoblich, M; Pratas Vital, V; Cardoso, D; Alves, F; Catela Mota, F; Casella, P

Introduc¸ão: Os pólipos fibroepiteliais do ureter são tumores benignos de origem mesodérmica extremamente raros em idade pediátrica, que podem causar obstruc¸ão da junc¸ão pieloureteral (JPU). Caso clínico: Os autores apresentam o caso de um doente do sexo masculino, de 11 anos de idade, referenciado por dor no flanco esquerdo intermitente associada a hidronefrose esquerda. Intraoperatoriamente, constatou-se a ...


Measuring and evaluating adjustment to retirement: a scoping review protocol

Pedreiro, A; Loureiro, H; Ferreira, M; Cardoso, D; Apóstolo, J

Review question/objective: The objective of this review is to identify the available methods and instruments that are used to measure adjustment to retirement among retirees. This review will also find studies that use other methodological approaches to evaluate, measure and/or understand adjustment to retirement. The following specific questions will be addressed by this review: What methods and instruments ar...


Hérnia de Spiegel Associada a Criptorquidia Homolateral - A Propósito de um Cas...

Vaz-Silva, A; Pratas-Vital, V; Alves, F; Cardoso, D; Catela-Mota, F; Casella, P

A hérnia de Spiegel (HS) é uma entidade clínica infrequente, sendo particularmente rara na criançaa. Embora possa associar-se a fatores adquiridos, na criança a maioria dos casos parece dever-se a alterações congénitas. A HS associa-se muitas vezes com outros defeitos congénitos, sendo a associação mais frequente a criptroquidia ipsilateral, observando-se com elevada frequência a presença do testículo no saco h...


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