11 documents found, page 1 of 2

O Papel da Medicina Interna numa Missão Humanitária em Guiné- Bissau

KYDNEY DISFUNTION AND HYPERTENSION – BEYOND THE OBVIOUS

Chronic kidney disease (CKD) is defined as the presence of an estimated glomerular filtration rate (eGFR) of less than 60mL/min/1.73m2 for 3 or more months, regardless of the cause. KDIGO (Kydney Disease Improving Global Outcomes) stages G3 to 5 have a prevalence of about 10% in the adult population. The risk factors that contribute the most to its onset and progression are arterial hypertension (HTN) and diabe...

WHEN HYPERTENSION “BLOWS AWAY ” – A CASE REPORT OF RENAL ARTERY ESTENOSIS

Secondary arterial hypertension (HTN), arises as a consequence of potentially treatable conditions, has an estimated prevalence of 5-10% in the hypertensive population. Approximately 85% cases are amongst individuals aged 40 and younger. The most common secondary etiologies vary by age group, with transversal renal parenchymal disease being present in all of them. Arterial hypertension of renal origin can be th...

Desvios laterais do eixo longitudinal de nado com e sem limitação da visão

Uma das causas da entropia do sistema biomecânico subjacente ao ato de andar ou correr é o desvio da linha do movimento, principalmente para os invisuais, sendo presumível que este fenómeno ocorra também na natação. O presente estudo teve como objetivo quantificar os desvios da linha longitudinal de nado em condições de visão normal e impedida. Nove nadadores de nível internacional (30,3± 4,76 anos, 180,1± 7,32...

General Perceptions Concerning Palliative Care

Palliative care, through a global and humanized approach, aims to improve the quality of life of those who face an incurable disease - the sick person, their caregivers and family members. The early recognition of these circumstances makes it possible to alleviate suffering, either physical, psychological, emotional or spiritual. This thematic is still often feared and avoided, thus the general concepts around ...

Avaliação da potência aeróbia e da velocidade máxima de nado jovens jogadores d...

O polo aquático é um desporto que solicita ambos os sistemas energéticos, razão pela qual o seu desenvolvimento e avaliação são fundamentais. Jogadores com melhor desempenho em testes de aptidão aeróbia conseguirão melhor resistir à fadiga específica do jogo, enquanto níveis elevados de velocidade serão decisivos para se propulsionarem e realizarem de forma veloz os movimentos acíclicos típicos do polo aquático...

A Nonribosomal Peptide Synthase Gene Driving Virulence in Mycobacterium tubercu...

Nonribosomal peptide synthases produce short peptides in a manner that is distinct from classical mRNA-dependent ribosome-mediated translation. The Mycobacterium tuberculosis genome harbors a nonribosomal peptide synthase gene, nrp, which is part of a gene cluster proposed to be involved in the biosynthesis of isonitrile lipopeptides. Orthologous clusters are found in other slow-growing pathogenic mycobacteria ...

Type I IFN inhibits alternative macrophage activation during mycobacterium tube...

Tuberculosis causes ∼1.5 million deaths every year, thus remaining a leading cause of death from infectious diseases in the world. A growing body of evidence demonstrates that type I IFN plays a detrimental role in tuberculosis pathogenesis, likely by interfering with IFN-γ–dependent immunity. In this article, we reveal a novel mechanism by which type I IFN may confer protection against Mycobacterium tuberculos...

Myeloid Sirtuin 2 expression does not impact long-term Mycobacterium tuberculos...

Sirtuins (Sirts) regulate several cellular mechanisms through deacetylation of several transcription factors and enzymes. Recently, Sirt2 was shown to prevent the development of inflammatory processes and its expression favors acute Listeria monocytogenes infection. The impact of this molecule in the context of chronic infections remains unknown. We found that specific Sirt2 deletion in the myeloid lineage tran...

Genetic diversity and population structure of Saccharomyces cerevisiae strains ...

We herein evaluate intraspecific genetic diversity of fermentative vineyard-associated S. cerevisiae strains and evaluate relationships between grape varieties and geographical location on populational structures. From the musts obtained from 288 grape samples, collected from two wine regions (16 vineyards, nine grape varieties), 94 spontaneous fermentations were concluded and 2820 yeast isolates were obtained ...