117 documents found, page 1 of 12

Association between lung function and dyspnoea and its variation in the multina...

Background: Dyspnoea is a common symptom of respiratory disease. However, data on its prevalence in general populations and its association with lung function are limited and are mainly from high-income countries. This study aimed to estimate the prevalence of dyspnoea across several world regions and to investigate the association of dyspnoea with lung function. Methods: Dyspnoea was assessed, and lung functio...

Concordance between FVC and FEV₆ for identifying chronic airflow obs...

Introduction: We investigated whether the forced expiratory volume in 6 s (FEV6) can be used as a surrogate for the forced vital capacity (FVC). Methods: The Burden of Obstructive Lung Disease is a multinational cohort study. At baseline, data were collected from adults aged 40 years or older, from 41 sites across 34 countries. Participants from 18 sites were followed up after a median of 8.3 years. Participant...

Current Progress of Activities at EU-SOLARIS ERIC: The European Research Infras...

ABSTRACT: An ERIC, established by a decision of the European Commission, is a legal entity possessing legal personality and full legal capacity acknowledged across all EU Member States. Its primary role is to establish and operate a research infrastructure on a non-economic basis. Under the initiative of Spain, France, Germany, and Cyprus as Members, with Portugal as an Observer, a European Research Infrastruct...

Ecotoxicity of the non-dioxin-like PCB-153 in the model marine diatom Phaeodact...

Despite the ban on polychlorinated biphenyls (PCBs) in developed countries since the 1930s, their persistence and use endured in developing countries, with reported toxic effects on various organisms. PCB congener 153 (PCB-153, 2, 2′, 4, 4′, 5, 5′–hexachlorobiphenyl) is notably prevalent in marine biota. However, its mode of action and impact on primary marine diatoms are not well documented. Phaeodactylum tric...

Como o trabalho do LNEG apoia a concretização do PNEC: Plano Nacional de Energi...

Activation profile of the Atlantic salmon (Salmo salar) calcium-sensing recepto...

In mammals, the calcium-sensing receptor (CaSR) is involved in nutrient sensing and modulated by several amino acids. In teleosts, sequence homologues of the mammalian CaSR have been described but their function in sensing amino acids remains elusive, including in Atlantic salmon (Salmo salar), an important aquaculture species. This study investigated the activation of Atlantic salmon Casr (asCasr)-mediated sig...

Seronegative Autoimmune Hepatitis / Primary Biliary Cholangitis Overlap Syndrom...

Continua por esclarecer se a síndrome de sobreposição representa uma variante da colangite biliar primária, da hepatite autoimune ou uma entidade clínica distinta. No presente artigo,apresentamos um caso clínico, delineando a marcha diagnóstica e a abordagem terapêutica de uma doente diagnosticada com esta patologia. Trata-se de uma mulher caucasiana de 64 anos, cujas manifestações clínicas abrangem característ...

NEWS4CSP Project: New coatings approaches to protect metallic materials from he...

Prevalence of chronic cough, its risk factors and population attributable risk ...

Background: Chronic cough is a common respiratory symptom with an impact on daily activities and quality of life. Global prevalence data are scarce and derive mainly from European and Asian countries and studies with outcomes other than chronic cough. In this study, we aimed to estimate the prevalence of chronic cough across a large number of study sites as well as to identify its main risk factors using a stan...

Persistent Organic Pollutants in Tagus Estuary Salt Marshes: Patterns of Contam...

The presence of anthropogenic compounds, including organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs), was studied in three salt marshes within the Tagus estuary, Portugal, along an anthropogenic pressure gradient. Results revealed differences in OCPs and PCBs among the marshes, with differing concentration levels. Specifically, one marsh, with surrounding agricultural activity, showed the hi...